Evidence map›Paper›PMID 28473034›Full record

ArticleMayo Clinic proceedings2017

Perceived Discrimination and Cardiovascular Outcomes in Older African Americans: Insights From the Jackson Heart Study.

Shannon M Dunlay, Steven J Lippmann, Melissa A Greiner, Emily C O'Brien, Alanna M Chamberlain, Robert J Mentz, Mario Sims

Abstract read
In one paragraph

Article in Mayo Clinic proceedings, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Racial/Ethnic Discrimination and Cardiometabolic Diseases: A Systematic Review.Journal of racial and ethnic health disparities · 2024
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Discrimination, religious affiliation, and arterial stiffness in African American women and men.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2024
    Article
  6. Article
  7. Everyday Discrimination Is Associated With Higher Odds of Hospitalizations Among Older African Americans.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
  8. Article
  9. The association of perceived discrimination with dementia risk in Black older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Multiple Reasons for Perceived Everyday Discrimination and All-Cause Mortality Risk Among Older Black Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Experiences of Discrimination Are Associated With Worse Metabolic Syndrome Severity Among African Americans in the Jackson Heart Study.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2021
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Shannon M DunlayMayo Clinic, Rochester, MN. Electronic address: dunlay.shannon@mayo.edu.
Steven J LippmannDuke Clinical Research Institute, Durham, NC.
Melissa A GreinerDuke Clinical Research Institute, Durham, NC.
Emily C O'BrienDuke Clinical Research Institute, Durham, NC.
Alanna M ChamberlainMayo Clinic, Rochester, MN.
Robert J MentzDuke Clinical Research Institute, Durham, NC.
Mario SimsUniversity of Mississippi Medical Center, Jackson.

Funding

A Collaboration for Improving Outcomes of African Americans with Heart FailureR01HL117305 · NHLBI · DUKE UNIVERSITY · PI CURTIS, LESLEY H, O'BRIEN, EMILY C · 2013 to 2016
$963k
End of Life Preferences and Healthcare Resource Use in Heart Failure PatientsK23HL116643 · NHLBI · MAYO CLINIC ROCHESTER · PI DUNLAY, SHANNON MARIE · 2013 to 2017
$739k
NHLBI NIH HHS HHSN268201300046CNHLBI NIH HHS HHSN268201300047CNHLBI NIH HHS HHSN268201300048CNHLBI NIH HHS HHSN268201300049CNHLBI NIH HHS HHSN268201300050CNHLBI NIH HHS K23 HL116643NHLBI NIH HHS R01 HL117305
6 · The paper itself

Abstract

objectiveTo assess the associations of perceived discrimination and cardiovascular (CV) outcomes in African Americans (AAs) in the Jackson Heart Study. PATIENTS AND

methodsIn 5085 AAs free of clinical CV disease at baseline enrolled in the Jackson Heart Study from September 26, 2000, through March 31, 2004, and followed through 2012, associations of everyday discrimination (frequency of occurrences of perceived unfair treatment) and lifetime discrimination (perceived unfair treatment in 9 life domains) with CV outcomes (all-cause mortality, incident coronary heart disease [CHD], incident stroke, and heart failure [HF] hospitalization) were examined using Cox proportional hazards regression models.

resultsHigher levels of everyday and lifetime discrimination were more common in participants who were younger and male and had higher education and income, lower perceived standing in the community, worse perceived health care access, and fewer comorbidities. Before adjustment, higher levels of everyday and lifetime discrimination were associated with a lower risk of all-cause mortality, incident CHD, stroke, and HF hospitalization. After adjustment for potential confounders, we found no association of everyday and lifetime discrimination with incident CHD, incident stroke, or HF hospitalization; however, a decrease in all-cause mortality with progressively higher levels of everyday discrimination persisted (hazard ratio per point increase in discrimination measure, 0.90; 95% CI, 0.82-0.99; P=.02). The unexpected association of everyday discrimination and all-cause mortality was partially mediated by perceived stress.

conclusionWe found no independent association of perceived discrimination with risk of incident CV disease or HF hospitalization in this AA population. An observed paradoxical negative association of everyday discrimination and all-cause mortality was partially mediated by perceived stress.

Indexed as

AgedAge DistributionBlack or African AmericanCardiovascular DiseasesCause of DeathChi-Square DistributionCoronary DiseaseFemaleHeart FailureHumansLongitudinal StudiesMaleMiddle AgedPerceptionProportional Hazards ModelsRisk Assessment

Identifiers

PMID28473034
PMCPMC5527992

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.