ArticleItalian journal of pediatrics2017
Efficacy and safety of early supplementation with 800 IU of vitamin D in very preterm infants followed by underlying levels of vitamin D at birth.
Article in Italian journal of pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03876704 (Effects of Fat-soluble Vitamins Supplementation in Early Life on Common Complications and Neural Development in Very Low Birth Weight Infants), which is not on this map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Fat-soluble Vitamins Supplementation in Early Life on Common Complications and Neural Development in Very Low Birth Weight Infants
Who cites it
18 citing papers in PubMed, 37 citations in OpenAlex.
- Monitored Supplementation of Vitamin D in Preterm Infants: A Randomized Controlled Trial.Nutrients · 2021Trial
- Trial
- Impact of different vitamin D supplementation doses on vitamin D status and bone metabolism in preterm infants.BMC pediatrics · 2026Article
- Effect of vitamin D supplementation on incidence of bronchopulmonary dysplasia among preterm infants up to 36 weeks' gestational age.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025Review
- Vitamin D: What We Know and What We Still Do Not Know About Vitamin D in Preterm Infants-A Literature Review.Children (Basel, Switzerland) · 2025Review
- Effects of high-dose vitamin D supplementation on bone mineral density in very low birth weight preterm infants.Frontiers in endocrinology · 2025Article
- Comparison of Daily Dose of 400 and 600 Units of Vitamin D in the Prevention of Osteopenia of Prematurity in Infants with a Gestational Age of Less Than and Equal to 32 Weeks.International journal of preventive medicine · 2024Article
- Vitamin d deficiency with high parathyroid hormone levels is related to late onset SEPSIS among preterm infants.BMC pregnancy and childbirth · 2023Article
- Breastfeeding and vitamin D.Clinical and experimental pediatrics · 2022Article
- Effects of Total Enteral Nutrition on Early Growth, Immunity, and Neuronal Development of Preterm Infants.Nutrients · 2021Review
- Vitamin D Status and Factors Associated with Vitamin D Deficiency during the First Year of Life in Preterm Infants.Nutrients · 2021Article
- Associated neonatal and maternal factors of osteopenia of prematurity in low resource setting: A cross-sectional study.Annals of medicine and surgery (2012) · 2021Article
- Prevalence of Vitamin D Deficiency Among Infants in Northern India: A Hospital Based Prospective Study.Cureus · 2020Article
- Association of vitamin D status at birth and respiratory outcomes in preterm infants.Korean journal of pediatrics · 2019Article
- Association between vitamin D level at birth and respiratory morbidities in very-low-birth-weight infants.Korean journal of pediatrics · 2019Article
- Advances in pediatrics in 2017: current practices and challenges in allergy, endocrinology, gastroenterology, genetics, immunology, infectious diseases, neonatology, nephrology, neurology, pulmonology from the perspective of Italian Journal of Pediatrics.Italian journal of pediatrics · 2018Review
- Vitamin D in pediatric age: consensus of the Italian Pediatric Society and the Italian Society of Preventive and Social Pediatrics, jointly with the Italian Federation of Pediatricians.Italian journal of pediatrics · 2018Review
- Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo determine the efficacy and safety of early supplementation with 800 IU of vitamin D in very low birth weight (VLBW) infants.
methodsSixty-six infants with a birth weight less than 1500 g admitted to the Neonatal Intensive Care Unit. Of these, 52 infants were eligible and received 800 IU/day vitamin D from 2 weeks of age. We examined 25-hydroxyvitamin-D (25[OH]D) levels from cord blood at birth and serum at 32 and 36 weeks of postmenstrual age.
resultsThe study infants were divided by cord-blood levels of 25(OH)D at birth into 25(OH)D concentrations < 10 ng/mL (n = 20) or ≥ 10 ng/mL (n = 29). Vitamin D intake of 800 IU/day safely achieved an 88% probability of vitamin D sufficiency at 36 weeks postmenstrual age in VLBW infants with cord-blood levels of 25(OH)D ≥ 10 ng/mL, and 65% probability of vitamin D sufficiency was observed in infants with 25 OHD concentrations < 10 ng/mL at birth.
conclusionConsidering the efficacy and safety of vitamin D supplementation in this study, vitamin D intake of 800 IU/day may enhance vitamin D status during early hospitalization in VLBW infants with 25 OHD concentrations < 10 ng/mL at birth. The clinical significance of optimal vitamin D intake in VLBW infants needs to be studied in larger controlled studies.
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