Evidence map›Paper›PMID 28472972›Full record

ReviewDiagnostic pathology2017

Primary Ewing's sarcoma/primitive neuroectodermal tumor of the ileum: case report of a 16-year-old Chinese female and literature review.

Teng Li, Fang Zhang, Yarui Cao, Shoubin Ning, Yongmin Bi, Weicheng Xue, Li Ren

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Diagnostic pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 45 citations in OpenAlex.

  1. Liver Ewing sarcoma: A case report.Radiology case reports · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Ewing sarcoma of the jejunum: A case report and literature review.World journal of gastrointestinal surgery · 2021
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Teng LiDepartment of Pathology, The General Hospital of Air force, PLA, Fucheng Road 30th, Beijing, China.
Fang ZhangDepartment of Pathology, The General Hospital of Air force, PLA, Fucheng Road 30th, Beijing, China.
Yarui CaoDepartment of Pathology, The General Hospital of Air force, PLA, Fucheng Road 30th, Beijing, China.
Shoubin NingDepartment of Gastroenterology, The General Hospital of Air force, PLA, Fucheng Road 30th, Beijing, China.
Yongmin BiDepartment of Radio and Imaging, The General Hospital of Air force, PLA, Fucheng Road 30th, Beijing, China.
Weicheng XueDepartment of Pathology, Beijing Cancer Hospital, Fucheng Road 52nd, Beijing, China.
Li RenDepartment of Pathology, The General Hospital of Air force, PLA, Fucheng Road 30th, Beijing, China. renlifei2000@sina.com.
Air Force General Hospital PLA · CNPeking University Cancer Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEwing's sarcoma (ES) and primitive neuroectodermal tumors (PNET) are closely related tumors. Although soft tissue ES/PNET are common in clinical practice, they are rare in the small intestine. Because of the absence of characteristic clinical symptoms, they are easily misdiagnosed as other benign or malignant diseases. CASE PRESENTATION: Here, we present the case of a 16-year-old female who complained of anemia and interval hematochezia. Her serum test results showed only a slight elevation of CA-125 and a low level of hemoglobin. Computer tomography and magnetic resonance imaging revealed a cystic and solid mass in the lower abdominal quadrant and pelvic region, which prompted suspicion of a malignant gastrointestinal stromal tumor of the small intestine. After resection, the tumor's histology and immunohistochemistry (positive for CD99, vimentin and synaptophysin) results suggested ES/PNET. Fluorescent in situ hybridization tests proved the breakpoint rearrangement of the EWSR1 gene in chr 22.Ultrastructural analysis revealed neurosecretory and glycogen granules in the tumor cell cytoplasm.

conclusionsTogether, these data supported the diagnosis of a rare case of localized ES/PNET in the small intestine without adjuvant chemo- or radiotherapy. To our knowledge, this is the first report from China of a primary small bowel ES/PNET in the English-language literature. In addition, on the basis of findings from previous publications and the current case, the optimal treatment for localized gastrointestinal ES/PNET is discussed.

Indexed as

AdolescentBiomarkers, TumorBiopsyChinaFemaleGene RearrangementHumansIleal NeoplasmsImmunohistochemistryIn Situ Hybridization, FluorescenceMagnetic Resonance ImagingNeuroectodermal Tumors, Primitive, PeripheralRNA-Binding Protein EWSSarcoma, EwingTomography, X-Ray ComputedBiomarkers, TumorEWSR1 protein, humanRNA-Binding Protein EWSEwing’s sarcomaEWS geneExtraosseousFISHPrimitive neuroectodermal tumorSmall intestine

Identifiers

PMID28472972
PMCPMC5418692
OpenAlexW2611849442

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.