ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2017
Gait Rather Than Cognition Predicts Decline in Specific Cognitive Domains in Early Parkinson's Disease.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.
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Who cites it
55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 101 citations in OpenAlex.
- Gait asymmetry in Parkinson's disease - a systematic review and meta-analysis (AsymmGait-Parkinson study).Scientific reports · 2026Pooled it
- Falls Self-Management Interventions for People with Parkinson's Disease: A Systematic Review.Journal of Parkinson's disease · 2019Pooled it
- Investigating Therapies for Freezing of Gait Targeting the Cognitive, Limbic, and Sensorimotor Domains.Neurorehabilitation and neural repair · 2021Trial
- Immediate and Long-Term Effectiveness of a Therapeutic Exercise Protocol in Patients with Dementia.Journal of clinical medicine · 2026Article
- Investigation of the validity, reliability and psychometric properties of the Turkish version of the Ottawa sitting scale in patients with Parkinson's disease.Scientific reports · 2025Article
- Correlation between gait parameters and clinical scales in individuals with Parkinson's disease.Dementia & neuropsychologia · 2025Article
- Modeling and validation of wearable sensor-based gait parameters in Parkinson's disease patients with cognitive impairment.Frontiers in aging neuroscience · 2025Article
- Longitudinal associations between physical performance and cognition in individuals with Parkinson's disease.Clinical parkinsonism & related disorders · 2025Article
- A wearable sensor and machine learning estimate step length in older adults and patients with neurological disorders.NPJ digital medicine · 2024Article
- Investigating underlying brain structures and influence of mild and subjective cognitive impairment on dual-task performance in people with Parkinson's disease.Scientific reports · 2024Article
- Neurocognitive Impairment and Social Cognition in Parkinson's Disease Patients.Neurology international · 2024Review
- Effect of musical cues on gait in individuals with Parkinson disease with comorbid dementia.Gait & posture · 2024Article
- Mild cognitive impairment in Parkinson's disease: current view.Frontiers in cognition · 2024Review
- Effects of rhythmic visual cues on cortical activation and functional connectivity features during stepping: an fNIRS study.Frontiers in human neuroscience · 2024Article
- Sonification for Personalised Gait Intervention.Sensors (Basel, Switzerland) · 2023Review
- Design of the STEPS trial: a phase II randomized controlled trial evaluating eHealth-supported motor-cognitive home training for Parkinson's disease.BMC neurology · 2023Article
- Free-water imaging of the cholinergic basal forebrain and pedunculopontine nucleus in Parkinson's disease.Brain : a journal of neurology · 2023Article
- Identification of a Gait Pattern for Detecting Mild Cognitive Impairment in Parkinson's Disease.Sensors (Basel, Switzerland) · 2023Article
- Safety and tolerability of adjunct non-invasive vagus nerve stimulation in people with parkinson's: a study protocol.BMC neurology · 2023Article
- Can Digital Mobility Assessment Enhance the Clinical Assessment of Disease Severity in Parkinson's Disease?Journal of Parkinson's disease · 2023Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundDementia is significant in Parkinson's disease (PD) with personal and socioeconomic impact. Early identification of risk is of upmost importance to optimize management. Gait precedes and predicts cognitive decline and dementia in older adults. We aimed to evaluate gait characteristics as predictors of cognitive decline in newly diagnosed PD.
methodsOne hundred and nineteen participants recruited at diagnosis were assessed at baseline, 18 and 36 months. Baseline gait was characterized by variables that mapped to five domains: pace, rhythm, variability, asymmetry, and postural control. Cognitive assessment included attention, fluctuating attention, executive function, visual memory, and visuospatial function. Mixed-effects models tested independent gait predictors of cognitive decline.
resultsGait characteristics of pace, variability, and postural control predicted decline in fluctuating attention and visual memory, whereas baseline neuropsychological assessment performance did not predict decline.
conclusionsThis provides novel evidence for gait as a clinical biomarker for PD cognitive decline in early disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.