ArticlePloS one2017
Serum biochemistry panels in African buffalo: Defining reference intervals and assessing variability across season, age and sex.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 31 citations in OpenAlex.
- Effects of Forage-to-Concentrate Ratio During Cold-Season Supplementation on Growth Performance, Serum Biochemistry, Hormones, and Antioxidant Capacity in Yak Calves on the Qinghai-Tibet Plateau.Animals : an open access journal from MDPI · 2025Article
- The Effects of Dietary Glycerol Fatty Acid Esters on the Production Performance, Serum Biochemistry, and Rumen Microbial Community of Crossbred Simmental Bulls.Animals : an open access journal from MDPI · 2025Article
- Dietary energy and protein gradients drive metabolic adaptation in growing-finishing yaks on the Qinghai-Tibet plateau.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- The heterogeneous herd: Drivers of close-contact variation in African buffalo and implications for pathogen invasion.Ecology and evolution · 2023Article
- Epidemiology ofInternational journal for parasitology. Parasites and wildlife · 2023Article
- Distinct life history strategies underpin clear patterns of succession in microparasite communities infecting a wild mammalian host.Molecular ecology · 2023Article
- Evaluation of haematological, serum biochemical and oxidative stress parameters in cattle naturally infected with lumpy skin disease virus.Tropical animal health and production · 2023Article
- Hematology and biochemistry of buffalo (Bubalus bubalis): influence of sex and age on reference values.Tropical animal health and production · 2021Article
- Diet and gut microbiome enterotype are associated at the population level in African buffalo.Nature communications · 2021Article
- Reference Intervals for Hematology and Clinical Chemistry for the African Elephant (Frontiers in veterinary science · 2021Article
- Physiological implications of life at the forest interface of oil palm agriculture: blood profiles of wild Malay civets (Conservation physiology · 2020Article
- Article
- Host immunity, nutrition and coinfection alter longitudinal infection patterns of schistosomes in a free ranging African buffalo population.PLoS neglected tropical diseases · 2017Article
- Detection of Pathogen Exposure in African Buffalo Using Non-Specific Markers of Inflammation.Frontiers in immunology · 2017Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Serum biochemical parameters can be utilized to evaluate the physiological status of an animal, and relate it to the animal's health. In order to accurately interpret individual animal biochemical results, species-specific reference intervals (RI) must be established. Reference intervals for biochemical parameters differ between species, and physiological differences including reproductive status, nutritional resource availability, disease status, and age affect parameters within the same species. The objectives of this study were to (1) establish RI for biochemical parameters in managed African buffalo (Syncerus caffer), (2) assess the effects of age, sex, pregnancy, and season on serum biochemistry values, and (3) compare serum biochemistry values from a managed herd to a free-ranging buffalo herd and to values previously published for captive (zoo) buffalo. Season profoundly affected all biochemistry parameters, possibly due to changes in nutrition and disease exposure. Age also affected all biochemical parameters except gamma glutamyl transferase and magnesium, consistent with patterns seen in cattle. Sex and reproductive status had no detectable effects on the parameters that were measured. The biochemical profiles of managed buffalo were distinct from those observed in the free-ranging herd and captive buffalo. Biochemical differences between buffalo from captive, managed, and free-ranging populations may be related to nutritional restriction or lack of predation in the context of management or captivity. The reference intervals provided in this study, in addition to the seasonal and age-related patterns observed, provide a foundation for health investigations that may inform management strategies in this ecologically and economically important species.
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