Evidence map›Paper›PMID 28472042›Full record

SynthesisPloS one2017

Mobile phone use and glioma risk: A systematic review and meta-analysis.

Ming Yang, WenWen Guo, ChunSheng Yang, JianQin Tang, Qian Huang, ShouXin Feng, AiJun Jiang, XiFeng Xu, Guan Jiang

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Cellular Phone Use and Risk of Tumors: Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2020
    Pooled it
  3. Review
  4. Review
  5. Trends in the incidence of brain cancer and the use of mobile phones: analysis of the Spanish Network of Cancer Registries (REDECAN).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
  6. Environmental Hazards and Glial Brain Tumors: Association or Causation?International journal of molecular sciences · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Do Cell Phones Cause Brain Tumors? Another Piece of the Puzzle.Journal of the National Cancer Institute · 2022
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. The correlation between polymorphisms in theTranslational pediatrics · 2021
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ming YangDepartment of Stereotactic Radiosurgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
WenWen GuoDepartment of Radiotherapy, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
ChunSheng YangDepartment of Dermatology, the Affiliated Huai'an Hospital of Xuzhou Medical University, Huai'an, China.
JianQin TangDepartment of Dermatology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Qian HuangDepartment of Radiotherapy, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
ShouXin FengDepartment of Stereotactic Radiosurgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
AiJun JiangDepartment of Stereotactic Radiosurgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
XiFeng XuDepartment of Stereotactic Radiosurgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Guan JiangDepartment of Dermatology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMany studies have previously investigated the potential association between mobile phone use and the risk of glioma. However, results from these individual studies are inconclusive and controversial. The objective of our study was to investigate the potential association between mobile phone use and subsequent glioma risk using meta-analysis.

methodsWe performed a systematic search of the Science Citation Index Embase and PubMed databases for studies reporting relevant data on mobile phone use and glioma in 1980-2016. The data were extracted and measured in terms of the odds ratio (OR) and 95% confidence interval (CI) using the random effects model. Subgroup analyses were also carried out. This meta-analysis eventually included 11 studies comprising a total 6028 cases and 11488 controls.

resultsThere was a significant positive association between long-term mobile phone use (minimum, 10 years) and glioma (OR = 1.44, 95% CI = 1.08-1.91). And there was a significant positive association between long-term ipsilateral mobile phone use and the risk of glioma (OR = 1.46, 95% CI = 1.12-1.92). Long-term mobile phone use was associated with 2.22 times greater odds of low-grade glioma occurrence (OR = 2.22, 95% CI = 1.69-2.92). Mobile phone use of any duration was not associated with the odds of high-grade glioma (OR = 0.81, 95% CI = 0.72-0.92). Contralateral mobile phone use was not associated with glioma regardless of the duration of use. Similarly, this association was not observed when the analysis was limited to high-grade glioma.

conclusionsOur results suggest that long-term mobile phone use may be associated with an increased risk of glioma. There was also an association between mobile phone use and low-grade glioma in the regular use or long-term use subgroups. However, current evidence is of poor quality and limited quantity. It is therefore necessary to conduct large sample, high quality research or better characterization of any potential association between long-term ipsilateral mobile phone use and glioma risk.

Indexed as

Cell PhoneBrain NeoplasmsGliomaHumansRisk Factors

Identifiers

PMID28472042
PMCPMC5417432

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.