Evidence map›Paper›PMID 28471944›Full record

ReviewAIDS (London, England)2017

Geriatric syndromes: new frontiers in HIV and sarcopenia.

Kellie L Hawkins, Todd T Brown, Joseph B Margolick, Kristine M Erlandson

Abstract readReview
In one paragraph

Review in AIDS (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 3 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 3 syntheses or guidelines pooled it, 80 citations in OpenAlex.

  1. Pooled it
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  11. Commentary on Quigley et al.Physiotherapy Canada. Physiotherapie Canada · 2024
    Article
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  13. Expert Consensus Statement on an Updated Definition of Unintended Weight Loss Among Persons With Human Immunodeficiency Virus in the Modern Treatment Era.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Kellie L HawkinsaUniversity of Colorado, Aurora, Colorado bJohns Hopkins School of Medicine cJohns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Todd T Brown
Joseph B Margolick
Kristine M Erlandson
Johns Hopkins University · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Colorado Denver · US

Funding

Multicenter Aids Cohort Study- Part B (Baltimore Site)U01AI035042 · NIAID · JOHNS HOPKINS UNIVERSITY · PI BROWN, TODD T, MARGOLICK, JOSEPH B. · 1993 to 2018
$61.5M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Wendy M Kohrt · 1995 to 2026
$32.6M
Center for the Analysis & Management of the Multicenter AIDS Cohort StudyUM1AI035043 · NIAID · JOHNS HOPKINS UNIVERSITY · PI D'SOUZA, GYPSYAMBER, JACOBSON, LISA P · 2012 to 2018
$20.7M
Predictors of Recovery and the App-Facilitated Tele-Rehabilitation (AFTER) Program for COVID SurvivorsR01AG054366 · NIA · UNIVERSITY OF COLORADO DENVER · PI ERLANDSON, KRISTINE MACE · 2016 to 2020
$3.4M
Mentoring in Endocrine and Metabolic Abnormalities in HIV and AgingK24AI120834 · NIAID · JOHNS HOPKINS UNIVERSITY · PI BROWN, TODD T · 2015 to 2025
$1.8M
Obesity and Cardiovascular Disease: Opportunity for Post-Doctoral TrainingT32HL116276 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ECKEL, ROBERT H · 2014 to 2018
$1.2M
The Impact of HIV and Aging on Physical Function and the Somatopause.K23AG050260 · NIA · UNIVERSITY OF COLORADO DENVER · PI ERLANDSON, KRISTINE MACE · 2014 to 2018
$946k
NHLBI NIH HHS T32 HL116276NIAID NIH HHS K24 AI120834NIAID NIH HHS U01 AI035042NIAID NIH HHS UM1 AI035043NIA NIH HHS K23 AG050260NIA NIH HHS R01 AG054366
6 · The paper itself

Abstract

: HIV infection, in many circumstances, can now be managed as a chronic disease due to the marked increase in life expectancy since the introduction of combination antiretroviral therapy (ART). As the patients who first had access to combination ART age into their 50s and 60s, the effects of chronic HIV infection on health have become an important research focus in HIV infection. People living with HIV appear to exhibit an earlier occurrence of some aging-related conditions compared to people without HIV, in part due to higher rates of comorbidities, high-risk behaviors (e.g. smoking, substance use), chronic immune activation, inflammation, and ART-specific factors. Some studies have even suggested an earlier-than-expected appearance of the 'geriatric syndromes,' which are complex medical syndromes of older adults that are associated with morbidity and mortality. The geriatric syndromes include a wide variety of disease processes ranging from incontinence and dementia to impairments in physical function. This review will focus on one geriatric syndrome, sarcopenia, in older HIV-infected populations, and its relation to other aging syndromes, including frailty and falls. The contribution of HIV itself, ART exposure, and specific comorbidities, and the importance of early recognition and prevention of these aging syndromes will be highlighted.

Indexed as

AgingDisease ManagementHIV InfectionsHumansSarcopenia

Identifiers

PMID28471944
PMCPMC5693390
OpenAlexW2610359815

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.