ArticleNature protocols2017
Improving your four-dimensional image: traveling through a decade of light-sheet-based fluorescence microscopy research.
Article in Nature protocols, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Strabismic imaging for correcting in-plane motion distortion in scanning imaging instruments and rolling shutter cameras.Advanced photonics · 2026Article
- Fifty high-content light sheet fluorescence microscopy datasets of Tribolium castaneum embryogenesis.Scientific data · 2025Article
- Metalens-Based Dual Light-Sheet Fluorescence Microscopy.Small methods · 2025Article
- Next generation marker-based vector concepts for rapid and unambiguous identification of single and double homozygous transgenic organisms.Biology open · 2023Article
- Advanced high resolution three-dimensional imaging to visualize the cerebral neurovascular network in stroke.International journal of biological sciences · 2022Review
- An adaptive microscope for the imaging of biological surfaces.Light, science & applications · 2021Article
- Single-objective high-resolution confocal light sheet fluorescence microscopy for standard biological sample geometries.Biomedical optics express · 2021Article
- Tutorial: guidance for quantitative confocal microscopy.Nature protocols · 2020Review
- A versatile, multi-laser twin-microscope system for light-sheet imaging.The Review of scientific instruments · 2020Article
- 3D Cell-Based Assays for Drug Screens: Challenges in Imaging, Image Analysis, and High-Content Analysis.SLAS discovery : advancing life sciences R & D · 2019Article
- Natural killer cells induce distinct modes of cancer cell death: Discrimination, quantification, and modulation of apoptosis, necrosis, and mixed forms.The Journal of biological chemistry · 2018Article
- Non-lethal genotyping of Tribolium castaneum adults using genomic DNA extracted from wing tissue.PloS one · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Light-sheet-based fluorescence microscopy features optical sectioning in the excitation process. This reduces phototoxicity and photobleaching by up to four orders of magnitude compared with that caused by confocal fluorescence microscopy, simplifies segmentation and quantification for three-dimensional cell biology, and supports the transition from on-demand to systematic data acquisition in developmental biology applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.