Evidence map›Paper›PMID 28471439›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2017

Relationships between cerebral autoregulation and markers of kidney and liver injury in neonatal encephalopathy and therapeutic hypothermia.

J K Lee, J Perin, C Parkinson, M O'Connor, M M Gilmore, M Reyes, J Armstrong, J M Jennings, F J Northington, R Chavez-Valdez

Open access · greenAbstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Cerebral autoregulation in pediatric and neonatal intensive care: A scoping review.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Utility of prenatal Doppler ultrasound to predict neonatal impaired cerebral autoregulation.Journal of perinatology : official journal of the California Perinatal Association · 2018
    Observational
  11. Review
  12. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

J K LeeDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
J PerinCenter for Child and Community Health Research (CCHR), Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, USA.
C ParkinsonNeurosciences Intensive Care Nursery, Johns Hopkins School of Medicine, Baltimore, MD, USA.
M O'ConnorDivision of Neonatology, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, USA.
M M GilmoreNeurosciences Intensive Care Nursery, Johns Hopkins School of Medicine, Baltimore, MD, USA.
M ReyesDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
J ArmstrongDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
J M JenningsCenter for Child and Community Health Research (CCHR), Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, USA.
F J NorthingtonNeurosciences Intensive Care Nursery, Johns Hopkins School of Medicine, Baltimore, MD, USA.
R Chavez-ValdezNeurosciences Intensive Care Nursery, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Johns Hopkins University · USJohns Hopkins Medicine · US

Funding

Translational Neuroscience CoreU54HD079123 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI VALLE, DAVID · 2014 to 2019
$7.9M
Imaging Neonatal Hypoxic Ischemic InjuryR01HD074593 · NICHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FRANCES J NORTHINGTON, JIANGYANG ZHANG · 2013 to 2026
$6.8M
Adult Biomarkers in Neonatal Brain Injury and DevelopmentR01HD086058 · NICHD · JOHNS HOPKINS UNIVERSITY · PI EVERETT, ALLEN D, NORTHINGTON, FRANCES J · 2016 to 2020
$3.1M
Mechanisms of Hypothermic Neuroprotection in NeonatesR01HD070996 · NICHD · JOHNS HOPKINS UNIVERSITY · PI NORTHINGTON, FRANCES J · 2012 to 2016
$1.7M
Injury of Hippocampal Interneurons following Neonatal Hypoxia-Ischemia and Therapeutic HypothermiaK08NS096115 · NINDS · JOHNS HOPKINS UNIVERSITY · PI CHAVEZ-VALDEZ, RAUL · 2017 to 2021
$1.2M
Neuronal injury after pediatric cardiac arrest, hypothermia, and rewarmingK08NS080984 · NINDS · JOHNS HOPKINS UNIVERSITY · PI LEE, JENNIFER KIM · 2014 to 2018
$960k
End-tidal carbon dioxide (ETCO2) directed cardiopulmonary resuscitation (CPR)R21HD072845 · NICHD · JOHNS HOPKINS UNIVERSITY · PI SHAFFNER, DONALD H · 2014 to 2015
$440k
NICHD NIH HHS R01 HD070996NICHD NIH HHS R01 HD074593NICHD NIH HHS R01 HD086058NICHD NIH HHS R21 HD072845NICHD NIH HHS U54 HD079123NINDS NIH HHS K08 NS080984NINDS NIH HHS K08 NS096115
6 · The paper itself

Abstract

objectiveWe studied whether cerebral blood pressure autoregulation and kidney and liver injuries are associated in neonatal encephalopathy (NE). STUDY

designWe monitored autoregulation of 75 newborns who received hypothermia for NE in the neonatal intensive care unit to identify the mean arterial blood pressure with optimized autoregulation (MAP

resultsGreater time with blood pressure within MAP

conclusionsBlood pressures that optimize cerebral autoregulation may support the kidneys. Blood pressures below MAP

Indexed as

Brain DiseasesInfant, Newborn, DiseasesLiver DiseasesArterial PressureCerebrovascular CirculationCreatinineFemaleHomeostasisHumansHypothermia, InducedInfant, NewbornLiver Function TestsMaleRenal InsufficiencyStatistics as TopicCreatinine

Identifiers

PMID28471439
PMCPMC5578902
OpenAlexW2611161574

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.