ArticleThe Angle orthodontist2017
Salivary leptin levels in normal weight and overweight individuals and their correlation with orthodontic tooth movement.
Article in The Angle orthodontist, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05988723 (Evaluation of the Effects of Obesity on Orthodontic Tooth Movement), which is not on this map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Effects of Obesity on Orthodontic Tooth Movement
Who cites it
19 citing papers in PubMed, 40 citations in OpenAlex.
- Leptin levels and skeletal response: exploring functional treatment efficacy in overweight vs. normal-weight Class II patients.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2026Article
- Cellular and Molecular Neuro-Bone Cell Interactions Drive Alveolar Bone Remodeling During Orthodontic Mechanical Loading.International journal of biological sciences · 2026Review
- High physical activity is associated with decreased fungiform papillae area and number, elevated sucrose recognition thresholds, and increased IL-6 levels: an observational human study.Nutrition & metabolism · 2025Article
- The Role of Adipokines and Gene Polymorphisms in the Development of Obesity- Induced Depression.Current obesity reports · 2025Review
- Evaluation of the effects of obesity on orthodontic tooth movement.Korean journal of orthodontics · 2025Article
- Consideration of hormonal changes for orthodontic treatment during pregnancy and lactation - a review.Reproductive biology and endocrinology : RB&E · 2024Review
- Impact of Leptin on the Expression Profile of Macrophages during Mechanical Strain In Vitro.International journal of molecular sciences · 2022Article
- Association of Orthodontic Tooth Movement with Leptin Concentration in Gingival Crevicular Fluid.Journal of pharmacy & bioallied sciences · 2022Article
- Article
- Linking leptin in GCF with tooth movement among Indians.Bioinformation · 2022Article
- Tooth movement, orofacial pain, and leptin, interleukin-1β, and tumor necrosis factor-α levels in obese adolescents.The Angle orthodontist · 2022Article
- Salivary Adipokine and Cytokine Levels as Potential Markers for the Development of Obesity and Metabolic Disorders.International journal of molecular sciences · 2021Review
- Leptin reduces in vitro cementoblast mineralization and survival as well as induces PGE2 release by ERK1/2 commitment.Clinical oral investigations · 2021Article
- Adiponectin, Leptin and Cardiovascular Disorders.Circulation research · 2021Review
- Effects of the multifunctional hormone leptin on orthodontic tooth movement in rats.American journal of translational research · 2020Article
- A cross-sectional cohort study of gingival crevicular fluid biomarkers in normal-weight and obese subjects during orthodontic treatment with fixed appliances.The Angle orthodontist · 2019Article
- The salivary levels of leptin and interleukin-6 as potential inflammatory markers in children obesity.PloS one · 2019Article
- Obesity attenuates force-induced tooth movement in mice with the elevation of leptin level: a preliminary translational study.American journal of translational research · 2018Article
- A Review of Selected Studies That Determine the Physical and Chemical Properties of Saliva in the Field of Dental Treatment.BioMed research international · 2018Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo assess and compare the concentration of leptin in saliva between normal weight and overweight individuals and to evaluate the rate of orthodontic tooth movement. MATERIALS AND
methodsThirty female subjects were divided into two groups: I (normal weight) and II (overweight group) based on their body mass index. All subjects underwent fixed appliance therapy requiring upper first premolar extraction and distal movement of the canine. Distal force was applied to the maxillary right canine using active lacebacks. Salivary samples were collected just before force application (T
resultsAt all three time intervals, mean leptin concentration was greater in overweight individuals than normal weight individuals. In both groups at T
conclusionsOverweight individuals had greater salivary leptin concentration. There was a positive correlation between salivary leptin concentration and rate of tooth movement in both normal and overweight individuals. The rate of tooth movement is decreased in overweight individuals as compared with normal weight individuals.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.