Evidence map›Paper›PMID 28471110›Full record

ArticleJournal of Zhejiang University. Science. B2017

Rapid quantification of multi-components in alcohol precipitation liquid of Codonopsis Radix using near infrared spectroscopy (NIRS).

Yu Luo, Wen-Long Li, Wen-Hua Huang, Xue-Hua Liu, Yan-Gang Song, Hai-Bin Qu

Abstract read
In one paragraph

Article in Journal of Zhejiang University. Science. B, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. [Application progress on near infrared spectroscopy in quality control and process monitoring of traditional Chinese medicine].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yu LuoPharmaceutical Informatics Institute, Zhejiang University, Hangzhou 310058, China.
Wen-Long LiPharmaceutical Informatics Institute, Zhejiang University, Hangzhou 310058, China.
Wen-Hua HuangLivzon (Group) Limin Pharmaceutical Factory, Shaoguan 512028, China.
Xue-Hua LiuLivzon (Group) Limin Pharmaceutical Factory, Shaoguan 512028, China.
Yan-Gang SongLivzon (Group) Limin Pharmaceutical Factory, Shaoguan 512028, China.
Hai-Bin QuPharmaceutical Informatics Institute, Zhejiang University, Hangzhou 310058, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A near infrared spectroscopy (NIRS) approach was established for quality control of the alcohol precipitation liquid in the manufacture of Codonopsis Radix. By applying NIRS with multivariate analysis, it was possible to build variation into the calibration sample set, and the Plackett-Burman design, Box-Behnken design, and a concentrating-diluting method were used to obtain the sample set covered with sufficient fluctuation of process parameters and extended concentration information. NIR data were calibrated to predict the four quality indicators using partial least squares regression (PLSR). In the four calibration models, the root mean squares errors of prediction (RMSEPs) were 1.22 μg/ml, 10.5 μg/ml, 1.43 μg/ml, and 0.433% for lobetyolin, total flavonoids, pigments, and total solid contents, respectively. The results indicated that multi-components quantification of the alcohol precipitation liquid of Codonopsis Radix could be achieved with an NIRS-based method, which offers a useful tool for real-time release testing (RTRT) of intermediates in the manufacture of Codonopsis Radix.

Indexed as

Models, StatisticalCodonopsisComplex MixturesComputer SimulationDrugs, Chinese HerbalEthanolFractional PrecipitationModels, ChemicalPlant ExtractsSolutionsSpectroscopy, Near-InfraredComplex MixturesDrugs, Chinese HerbalEthanolPlant ExtractsSolutionsNear infrared spectroscopy; Codonopsis Radix; Alcohol precipitation; Real-time release testing; Multi-components quantification

Identifiers

PMID28471110
PMCPMC5442981

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.