ArticleHuman brain mapping2017
Language ability in preterm children is associated with arcuate fasciculi microstructure at term.
Article in Human brain mapping, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.
- Language outcome related to brain structures in school-aged preterm children: A systematic review.PloS one · 2018Pooled it
- Language laterality and cognitive skills: does anatomy matter?Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Tract-specific white matter microstructure associated with early cognitive development in infants.Neuroimage. Reports · 2026Article
- A Novel Fixel-Based Approach for Resolving Neonatal White Matter Microstructure from Clinical Diffusion MRI.medRxiv : the preprint server for health sciences · 2026Article
- A novel fixel-based approach for resolving neonatal white matter microstructure from clinical diffusion MRI.Frontiers in neuroscience · 2026Article
- The auditory environment drives superior temporal sulcus depth in the neonatal period.Brain structure & function · 2025Article
- Prenatal Adversity and Neonatal White Matter Microstructure Independently Relate to Language Outcomes at Age 2 Years.The Journal of pediatrics · 2025Article
- Functional connectivity of the superior temporal sulcus at term-equivalent age: effects of gestational age and sex.Brain structure & function · 2025Article
- Methodological considerations on diffusion MRI tractography in infants aged 0-2 years: a scoping review.Pediatric research · 2025Article
- Developmental Trajectories and Differences in Functional Brain Network Properties of Preterm and At-Term Neonates.Human brain mapping · 2025Article
- Neonatal inflammation and near-term white matter microstructure in infants born very preterm.Neuroimage. Reports · 2024Article
- Applications of advanced diffusion MRI in early brain development: a comprehensive review.Brain structure & function · 2023Review
- Language Experience during Infancy Predicts White Matter Myelination at Age 2 Years.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Neuroimaging of brain connectivity related to reading outcomes in children born preterm: A critical narrative review.Frontiers in pediatrics · 2023Review
- Microstructural alterations in association tracts and language abilities in schoolchildren born very preterm and with poor fetal growth.Pediatric radiology · 2023Article
- White matter association tracts underlying language and theory of mind: An investigation of 809 brains from the Human Connectome Project.NeuroImage · 2022Article
- Language input in late infancy scaffolds emergent literacy skills and predicts reading related white matter development.Frontiers in human neuroscience · 2022Article
- Advances in functional and diffusion neuroimaging research into the long-term consequences of very preterm birth.Journal of perinatology : official journal of the California Perinatal Association · 2021Review
- Neonatal white matter tract microstructure and 2-year language outcomes after preterm birth.NeuroImage. Clinical · 2020Article
- Age of Speech Onset in Autism Relates to Structural Connectivity in the Language Network.Cerebral cortex communications · 2020Article
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
Abstract
In the mature human brain, the arcuate fasciculus mediates verbal working memory, word learning, and sublexical speech repetition. However, its contribution to early language acquisition remains unclear. In this work, we aimed to evaluate the role of the direct segments of the arcuate fasciculi in the early acquisition of linguistic function. We imaged a cohort of 43 preterm born infants (median age at birth of 30 gestational weeks; median age at scan of 42 postmenstrual weeks) using high b value high-angular resolution diffusion-weighted neuroimaging and assessed their linguistic performance at 2 years of age. Using constrained spherical deconvolution tractography, we virtually dissected the arcuate fasciculi and measured fractional anisotropy (FA) as a metric of white matter development. We found that term equivalent FA of the left and right arcuate fasciculi was significantly associated with individual differences in linguistic and cognitive abilities in early childhood, independent of the degree of prematurity. These findings suggest that differences in arcuate fasciculi microstructure at the time of normal birth have a significant impact on language development and modulate the first stages of language learning. Hum Brain Mapp 38:3836-3847, 2017. © 2017 Wiley Periodicals, Inc.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.