Evidence map›Paper›PMID 28470858›Full record

ArticleMagnetic resonance in medicine2018

Choice of reference measurements affects quantification of long diffusion time behaviour using stimulated echoes.

Michiel Kleinnijenhuis, Jeroen Mollink, Wilfred W Lam, Paul Kinchesh, Alexandre A Khrapitchev, Sean C Smart, Saad Jbabdi, Karla L Miller

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michiel KleinnijenhuisOxford Centre for Functional MRI of the Brain, University of Oxford, Oxford, United Kingdom.ORCID 0000-0003-3036-4326
Jeroen MollinkOxford Centre for Functional MRI of the Brain, University of Oxford, Oxford, United Kingdom.
Wilfred W LamOxford Centre for Functional MRI of the Brain, University of Oxford, Oxford, United Kingdom.
Paul KincheshCancer Research UK & Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, United Kingdom.
Alexandre A KhrapitchevCancer Research UK & Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, United Kingdom.
Sean C SmartCancer Research UK & Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, United Kingdom.
Saad JbabdiOxford Centre for Functional MRI of the Brain, University of Oxford, Oxford, United Kingdom.
Karla L MillerOxford Centre for Functional MRI of the Brain, University of Oxford, Oxford, United Kingdom.

Funding

Cancer Research UK C5255/A15935Medical Research Council MR/K02213X/1Medical Research Council MR/L009013/1Medical Research Council MR/L022656/1Wellcome Trust 091509/Z/10/Z
6 · The paper itself

Abstract

purposeTo demonstrate how reference data affect the quantification of the apparent diffusion coefficient (ADC) in long diffusion time measurements with diffusion-weighted stimulated echo acquisition mode (DW-STEAM) measurements, and to present a modification to avoid contribution from crusher gradients in DW-STEAM.

methodsFor DW-STEAM, reference measurements at long diffusion times have significant b

resultsCalculations of biexponential diffusion decay show that the ADC is underestimated for reference images with b > 0, which can induce an apparent time-dependence for fixed-q

conclusionsVariation in the b-value of reference measurements in DW-STEAM can induce artificial diffusion time dependence in ADC, even in the absence of restriction. Magn Reson Med 79:952-959, 2018. © 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Indexed as

Corpus CallosumDiffusion Magnetic Resonance ImagingHumansSignal Processing, Computer-Assistedapparent diffusion coefficientbiexponential diffusiondiffusion timerestrictionstimulated echo

Identifiers

PMID28470858
PMCPMC5811793

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.