ArticleJournal of neurology2017
Japanese encephalitis can trigger anti-N-methyl-D-aspartate receptor encephalitis.
Article in Journal of neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Spectrum of movement disorders in Japanese encephalitis: a systematic review of case reports, case series, and cohort studies.Acta neurologica Belgica · 2026Pooled it
- Anti-NMDA Receptor Encephalitis, Human Papillomavirus, and microRNA.Current medicinal chemistry · 2025Pooled it
- Japanese encephalitis: Current status, recent progress, and persistent challenges.PLoS neglected tropical diseases · 2026Review
- Acute neuronal cell death and neuroinflammation per se do not trigger secondary autoimmune encephalitis in mice.Scientific reports · 2025Article
- Anti-NMDA receptor encephalitis following Murray Valley encephalitis: a case report.ASM case reports · 2025Article
- Antibodies in neurological diseases: Established, emerging, explorative.Immunological reviews · 2024Review
- Antibody-positive autoimmune encephalitis and paraneoplastic neurological syndrome: A Swedish case series.Brain and behavior · 2024Article
- The immunobiology of herpes simplex virus encephalitis and post-viral autoimmunity.Brain : a journal of neurology · 2024Review
- Article
- Neuroinvasion of emerging and re-emerging arboviruses: A scoping review.SAGE open medicine · 2024Article
- Mice as an Animal Model for Japanese Encephalitis Virus Research: Mouse Susceptibility, Infection Route, and Viral Pathogenesis.Pathogens (Basel, Switzerland) · 2023Review
- [Clinical features of autoimmune encephalitis secondary to epidemic encephalitis B in 5 children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023Article
- The presence of human respiratory syncytial virus in the cerebrospinal fluid of a child with Anti-N-methyl-D-aspartate receptor encephalitis of unknown trigger.Virology journal · 2023Article
- Detection and significance of neuronal autoantibodies in patients with meningoencephalitis in Vientiane, Lao PDR.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2022Article
- Nervous System Manifestations of Arboviral Infections.Current tropical medicine reports · 2022Review
- De Novo Movement Disorders and COVID-19: Exploring the Interface.Movement disorders clinical practice · 2021Review
- First report of concomitant cryptococcal meningitis and anti-NMDAR encephalitis.Brain, behavior, & immunity - health · 2020Article
- Post-infectious neurological disorders.Therapeutic advances in neurological disorders · 2020Review
- Japanese encephalitis - the prospects for new treatments.Nature reviews. Neurology · 2018Review
- Anti-NMDAR Encephalitis in Association with Herpes Simplex Virus and Viral and Bacterial Zoonoses.Annals of Indian Academy of NeurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Japanese encephalitis (JE) is usually a monophasic disease; however, in rare cases, patients with JE may have an early relapse after a partial recovery, giving rise to a biphasic pattern for the disease. In this study, we report three pediatric cases in which post-JE relapse was characterized by movement disorder and/or behavioral problems, and was related to anti-N-methyl-D-aspartate receptor (NMDAR) immunoglobulin G (IgG). Serum and cerebrospinal fluid were examined for anti-NMDAR IgG in three patients who had confirmed JE and then developed relapsing symptoms which were similar to those of anti-NMDAR encephalitis. The main symptoms of the two young children were choreoathetosis, irritability, and sleep disorder; while for the teenager, agitation, mutism, rigidity, and sleep disorder were the main symptoms. Samples of cerebrospinal fluid from all patients were positive for anti-NMDAR IgG, and all patients gradually improved with immunotherapy. Testing for NMDAR antibodies is highly recommend in patients with JE, especially those with a relapsing syndrome involving movement disorder and/or behavioral problems, as these patients may benefit from immunotherapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.