Evidence map›Paper›PMID 28470568›Full record

ArticleNeurotoxicity research2018

The Evaluation of BMAA Inhalation as a Potential Exposure Route Using a rat Model.

Laura Louise Scott, Simoné Downing, Timothy Grant Downing

Abstract read
PubMed Publisher
In one paragraph

Article in Neurotoxicity research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Environmental Neurotoxin β-Microorganisms · 2022
    Review
  5. Cyanobacteria, Cyanotoxins, and Neurodegenerative Diseases:International journal of molecular sciences · 2021
    Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Laura Louise ScottDepartment of Biochemistry and Microbiology, Nelson Mandela Metropolitan University, PO Box 77 000, Port Elizabeth, 6031, South Africa.
Simoné DowningDepartment of Biochemistry and Microbiology, Nelson Mandela Metropolitan University, PO Box 77 000, Port Elizabeth, 6031, South Africa.
Timothy Grant DowningDepartment of Biochemistry and Microbiology, Nelson Mandela Metropolitan University, PO Box 77 000, Port Elizabeth, 6031, South Africa. Tim.Downing@nmmu.ac.za.
Nelson Mandela University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic inhalation of aerosolized β-N-methylamino-L-alanine (BMAA) could serve as potenital route for exposure to this cyanobacterial neurotoxin implicated in the development of neurodegenerative disease. We investigated environmental aerosol BMAA loads and the fate of inhaled isotopically labeled aerosolized BMAA in adult male Sprague Dawley rats, with doses corresponding to chronic aerosolized environmental BMAA exposure of over 65 days and up to 266 years. Environmental BMAA aerosol concentrations ranged from 6-39 pg L¯

Indexed as

Inhalation ExposureAmino Acids, DiaminoAnimalsCyanobacteria ToxinsDisease Models, AnimalDose-Response Relationship, DrugGlutamic AcidGlutamineMaleNecrosisNeurotoxicity SyndromesNeurotoxinsRatsRats, Sprague-DawleyTime FactorsTissue DistributionAmino Acids, Diaminobeta-N-methylamino-L-alanineCyanobacteria ToxinsGlutamic AcidGlutamineNeurotoxinsTritium2,3-diaminopropanoic acidBMAAInhalation exposureMetabolismRatβ-N-methylamino-L-alanine

Identifiers

PMID28470568
OpenAlexW2610237131

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.