Evidence map›Paper›PMID 28470535›Full record

ArticleMedical oncology (Northwood, London, England)2017

Clinical impact of cone beam computed tomography on iterative treatment planning during ultrasound-guided percutaneous ablation of liver malignancies.

Chiara Floridi, Alessandro Radaelli, Filippo Pesapane, Enrico Maria Fumarola, Michela Lecchi, Andrea Agostini, Andrea Giovagnoni, Gianpaolo Carrafiello, Bradford Wood

Abstract read
PubMed Publisher
In one paragraph

Article in Medical oncology (Northwood, London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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  9. Diagnostic and interventional radiology: an update.Acta bio-medica : Atenei Parmensis · 2020
    Article
  10. Imaging guided percutaneous renal biopsy: do it or not?Acta bio-medica : Atenei Parmensis · 2020
    Article
  11. Basic embolization techniques: tips and tricks.Acta bio-medica : Atenei Parmensis · 2020
    Review
  12. Review
  13. Hepatic tumors: pitfall in diagnostic imaging.Acta bio-medica : Atenei Parmensis · 2020
    Review
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Chiara FloridiAzienda Ospedaliera Fatebenefratelli e Oftalmico, Milan, Italy. chiara.floridi@gmail.com.
Alessandro RadaelliImage-Guided Therapy Systems, Philips Healthcare, Best, The Netherlands.
Filippo PesapaneDepartment of Health Sciences, Diagnostic and Interventional Radiology, San Paolo Hospital, University of Milan, Milan, Italy.
Enrico Maria FumarolaDepartment of Health Sciences, Diagnostic and Interventional Radiology, San Paolo Hospital, University of Milan, Milan, Italy.
Michela LecchiHealth Physics, San Paolo Hospital, University of Milan, Milan, Italy.
Andrea AgostiniDepartment of Radiology, School of Radiology, Università Politecnica delle Marche, Ancona, Italy.
Andrea GiovagnoniDepartment of Radiology, School of Radiology, Università Politecnica delle Marche, Ancona, Italy.
Gianpaolo CarrafielloDepartment of Health Sciences, Diagnostic and Interventional Radiology, San Paolo Hospital, University of Milan, Milan, Italy.
Bradford WoodRadiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, USA.
Marche Polytechnic University · ITOspedale San Paolo · ITUniversity of Milan · ITAzienda Ospedaliera Fatebenefratelli e Oftalmico · ITNational Institutes of Health · USPhilips (Netherlands) · NL

Funding

Center for Interventional OncologyZIDBC011242 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI WOOD, BRADFORD J · 2009 to 2025
$18.7M
Navigation Tools for Image Guided Minimally invasive TherapiesZIACL040011 · CLC · CLINICAL CENTER · PI WOOD, BRADFORD · 2009 to 2025
$0k
Interventional OncologyZIACL040015 · CLC · CLINICAL CENTER · PI WOOD, BRADFORD · 2009 to 2025
$0k
6 · The paper itself

Abstract

A standardized cone beam computed tomography (CBCT) protocol may impact optimal ablation probe(s) positioning during ultrasound-guided microwave ablation (MWA). To evaluate this hypothesis, 15 patients underwent ultrasound-guided percutaneous MWA of 15 liver lesions (10 hepatocellular carcinomas, 5 metastasis ranging 11-41 mm) with the ultrasound guidance assisted by a dedicated CBCT protocol. Pre-procedural enhanced CBCT (ceCBCT) was performed after intravenous contrast administration to visualize the lesion and determine the optimal approach using CBCT-based ablation planning software. MW antennas were positioned under ultrasound guidance, and non-enhanced CBCT was performed after deployment and fused with pre-procedural ceCBCT to assess tumor targeting and modify subsequent steps of the procedure. CBCT lesion detection accuracy and number of needle repositioning on the basis of CBCT information were recorded. Clinical success was measured on 1-month follow-up contrast-enhanced CT. The target lesion was detected on ceCBCT in 13 out of 15 patients (87%). The undetected lesions were only visible on diagnostic contrast-enhanced magnetic resonance imaging, which was then fused to the CBCT and fluoroscopy to facilitate targeting. MW antennas were repositioned on the basis of CBCT in 11 lesions (73%). Clinical success was achieved in 14/15 ablations (93%) with a mean follow-up of X months. The only case of local recurrence was expected, as the intent was tumor debulking. CBCT imaging during ultrasound-guided liver ablation is feasible and leads to ablation device repositioning in the majority of cases.

Indexed as

Catheter AblationCone-Beam Computed TomographyHumansLiverLiver NeoplasmsMaleMiddle AgedProspective StudiesSurgery, Computer-AssistedUltrasonography, InterventionalCone beam CTLiver malignanciesMicrowave ablationPercutaneous ablation

Identifiers

PMID28470535
OpenAlexW2610253461

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.