ReviewCurrent psychiatry reports2017
Biomarkers of Suicide Attempt Behavior: Towards a Biological Model of Risk.
Review in Current psychiatry reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
111 citing papers in PubMed, 8 syntheses or guidelines pooled it, 227 citations in OpenAlex.
- Identification of suicide brain transcriptomic signatures using meta-analysis of multiple cohorts.Translational psychiatry · 2026Pooled it
- The association between white matter hyperintensities and suicide attempts in affective disorders: a systematic review and meta-analysis.Translational psychiatry · 2025Pooled it
- Peripheral blood cellular immunophenotype in suicidal ideation, suicide attempt, and suicide: a systematic review and meta-analysis.Molecular psychiatry · 2024Pooled it
- Inflammation and nitro-oxidative stress in current suicidal attempts and current suicidal ideation: a systematic review and meta-analysis.Molecular psychiatry · 2022Pooled it
- Functional alterations of the suicidal brain: a coordinate-based meta-analysis of functional imaging studies.Brain imaging and behavior · 2022Pooled it
- Cannabinoid Receptors, Mental Pain and Suicidal Behavior: a Systematic Review.Current psychiatry reports · 2018Pooled it
- The association between electrodermal activity (EDA), depression and suicidal behaviour: A systematic review and narrative synthesis.BMC psychiatry · 2018Pooled it
- Neural Correlates Involved in Behavioral Metrics of Emotion Regulation and Suicidal Thoughts and Behaviors.Archives of suicide research : official journal of the International Academy for Suicide ResearchPooled it
- Association Between Peripheral Inflammatory and Hematological Markers and Suicide Attempts: A Retrospective Case-Control Study.Psychiatry investigation · 2026Article
- Using Automated Coding of Nonverbal Behavior During a Suicide Assessment to Inform Risk Detection: Mixed Cross-Sectional and Exploratory Prospective Study.JMIR formative research · 2026Article
- Developmental predictors of suicide attempts from childhood to early adulthood: a 15-year prospective cohort study.Lancet regional health. Americas · 2026Article
- Investigating NF-κB as a biomarker for suicidal ideation in depression in a pilot case-control study.Discover mental health · 2026Article
- The kynurenine pathway in depression and schizophrenia: convergent signals, divergent states, and clinical signatures.EXCLI journal · 2026Review
- The use of multidimensional assessment in developmental age: How evaluation of the emotional-autonomic state can facilitate the differential diagnosis in psychopathology. Description of two case studies.Health psychology report · 2026Article
- Differentiating suicide risk in treatment-resistant depression: clinical and functional imaging correlates of suicidal ideation and attempt.NeuroImage. Clinical · 2026Article
- Novel insights into gut microbiota alterations in major depressive disorder with suicidal ideation: a metagenomic analysis.Frontiers in microbiology · 2026Article
- The prospect of suicide biomarkers: from neurobiology to precision prevention.Frontiers in psychology · 2026Review
- A biological phenotype of suicide attempt in adolescents with nonsuicidal self-injury: a machine-based learning approach.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Randomized, placebo-controlled, double-blind clinical trial on the contributions of vitamin D in the control of cardiovascular risk factors, depressive symptoms and suicide risk.American heart journal plus : cardiology research and practice · 2025Article
- Altered gut microbial diversity, composition, and metabolomic potential in patients with major depressive disorder and recent suicide attempt.Brain, behavior, & immunity - health · 2025Article
51 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewThe rising suicide rate in the USA will not be reversed without improved risk assessment and prevention practices. To date, the best method for clinicians to assess a patient's risk for suicide is screening for past suicide attempts in the patient and their family. However, neuroimaging, genomic, and biochemical studies have generated a body of findings that allow description of an initial heuristic biological model for suicidal behavior that may have predictive value. RECENT
findingsWe review studies from the past 3 years examining potential biological predictors of suicide attempt behavior. We divide findings into two major categories: (1) structural and functional brain imaging findings and (2) biochemical and genomic findings encompassing several systems, including major neurotransmitters (serotonin, catecholamines, GABA, and glutamate), the hypothalamic pituitary adrenal (HPA) axis, the inflammasome, lipids, and neuroplasticity. The biomarkers that appear promising for assessing suicide risk in clinical settings include indices of serotonergic function, inflammation, neuronal plasticity, and lipids.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.