ReviewIntensive care medicine2017
The ICM research agenda on extracorporeal life support.
Review in Intensive care medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Hospital Costs of Extracorporeal Membrane Oxygenation in Adults: A Systematic Review.PharmacoEconomics - open · 2021Pooled it
- Obesity as a Risk Factor for Failure to Wean from ECMO: A Systematic Review and Meta-Analysis.Canadian respiratory journal · 2021Pooled it
- Multiparameters associated to successful weaning from VA ECMO in adult patients with cardiogenic shock or cardiac arrest: Systematic review and meta-analysis.Annals of cardiac anaesthesiaPooled it
- Impact of extracorporeal circuits on systemic drug levels - a scoping review.Journal of anesthesia, analgesia and critical care · 2026Review
- Full percutaneous decannulation of VA-ECMO using MANTACritical care (London, England) · 2026Article
- Clinical correlates for major bleeding during veno-arterial extracorporeal membrane oxygenation support: a time-dependent perspective.Critical care (London, England) · 2026Article
- Data-driven subphenotyping of severe ARDS patients requiring VV-ECMO.Frontiers in digital health · 2026Article
- Prolonged Thromboelastography R Time and Thrombocytopenia as Early Warning Indicators of Bleeding in ECMO Patients Who Developed Sepsis During Support: A Retrospective Cohort Study.Infection and drug resistance · 2026Article
- Mortality and complications in low-dose vs standard-dose unfractionated heparin anticoagulation for extracorporeal membrane oxygenation: a systematic review and meta-analysis.Research and practice in thrombosis and haemostasis · 2026Article
- Redefining weaning in a VA ECMO: a case report on pump-controlled retrograde trial off.Indian journal of thoracic and cardiovascular surgery · 2025Article
- Staying in Place: In Vitro Comparison of Extracorporeal Membrane Oxygenation Cannula Fixation for Dislodgment Prevention.Journal of clinical medicine · 2025Article
- ECMO for bridging lung transplantation.European journal of medical research · 2024Review
- Mechanical Circulatory Support Devices in Patients with High-Risk Pulmonary Embolism.Journal of clinical medicine · 2024Review
- Age and associated outcomes among patients receiving venovenous extracorporeal membrane oxygenation for acute respiratory failure: analysis of the Extracorporeal Life Support Organization registry.Intensive care medicine · 2024Article
- Subtypes and Mechanistic Advances of Extracorporeal Membrane Oxygenation-Related Acute Brain Injury.Brain sciences · 2023Review
- Inadequate Energy Delivery Is Frequent among COVID-19 Patients Requiring ECMO Support and Associated with Increased ICU Mortality.Nutrients · 2023Article
- Medical nutrition therapy in patients receiving extracorporeal membrane oxygenation: knowledge in progress.Archivos de cardiologia de Mexico · 2023Article
- Article
- Changes of Coagulation and Fibrinolytic Status Detected by Thromboelastography (TEG6sHealthcare (Basel, Switzerland) · 2022Article
- Extracorporeal carbon dioxide removal for acute respiratory failure: a review of potential indications, clinical practice and open research questions.Intensive care medicine · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to concisely describe the current standards of care, major recent advances, common beliefs that have been contradicted by recent trials, areas of uncertainty, and clinical studies that need to be performed over the next decade and their expected outcomes with regard to extracorporeal membrane oxygenation (ECMO).
methodsNarrative review based on a systematic analysis of the medical literature, national and international guidelines, and expert opinion.
resultsThe use of venovenous ECMO (VV-ECMO) is increasing in the most severe forms of acute lung injury. In patients with cardiogenic shock, short-term veno-arterial ECMO (VA-ECMO) provides both pulmonary and circulatory support. Technological improvements and recently published studies suggest that ECMO is able to improve patients' outcomes. There are, however, many uncertainties regarding the real benefits of this technique both in hemodynamic and respiratory failure, the territorial organization to deliver ECMO, the indications and the use of concomitant treatments.
conclusionsAlthough there have been considerable advances regarding the use of ECMO in critically ill patients, the risk/benefit ratio remains underinvestigated. ECMO indications, organization of ECMO delivery, and use of adjuvant therapeutics need also to be explored. Ongoing and future studies may be able to resolve these issues.
Indexed as
Identifiers
28470346What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.