Evidence map›Paper›PMID 28470279›Full record

ArticleOrganic & biomolecular chemistry2017

Synthesis of cyclooxygenase metabolites of 8,9-epoxyeicosatrienoic acid (EET): 11- and 15-hydroxy 8,9-EETs.

Bogdan Barnych, Amy A Rand, Tomas Cajka, Kin Sing Stephen Lee, Bruce D Hammock

Abstract read
In one paragraph

Article in Organic & biomolecular chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  3. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Bogdan BarnychDepartments of Entomology and Nematology and UC Davis Comprehensive Cancer Center, University of California Davis, One Shields Avenue, Davis, California 95616, USA. bdhammock@ucdavis.edu.
Amy A Rand
Tomas Cajka
Kin Sing Stephen Lee
Bruce D Hammock
UC Davis Comprehensive Cancer CenterUniversity of California, Davis · US

Funding

Workshop on Environmental Technology Transfer and EntrepreneurshipP42ES004699 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI CHIAMVIMONVAT, NIPAVAN · 1987 to 2021
$50.1M
Training and Education CoreU54NS079202 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ROGAWSKI, MICHAEL A. · 2012 to 2021
$35.7M
West Coast Central Comprehensive Metabolomics Resource Core (WC3MRC)U24DK097154 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FIEHN, OLIVER · 2012 to 2017
$9.9M
Functional Cardio-MetabolomicsP20HL113452 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI HAZEN, STANLEY L, TANG, WAI HONG WILSON · 2012 to 2016
$4.8M
HYDROLYTIC ENZYMES IN THE METABOLISM OF TOXINSR01ES002710 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI HAMMOCK, BRUCE D · 1985 to 2018
$4.0M
Training Program in Oncogenic Signals and Chromosome BiologyT32CA108459 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HEYER, WOLF-DIETRICH · 2006 to 2020
$3.6M
Identifying the receptors of environmentally sensitive epoxy-eicosanoids with AMSR00ES024806 · NIEHS · MICHIGAN STATE UNIVERSITY · PI LEE, KIN SING STEPHEN · 2017 to 2019
$727k
Metabolomics: an accurate mass GC-DART AccuTOF mass spectrometer for routine idenS10RR031630 · NCRR · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FIEHN, OLIVER · 2011 to 2011
$260k
NCI NIH HHS T32 CA108459NCRR NIH HHS S10 RR031630NHLBI NIH HHS P20 HL113452NIDDK NIH HHS U24 DK097154NIEHS NIH HHS P42 ES004699NIEHS NIH HHS R00 ES024806NIEHS NIH HHS R01 ES002710NINDS NIH HHS U54 NS079202
6 · The paper itself

Abstract

COX metabolites of 8,9-EET, previously observed as potent mitogenic lipid mediators, were synthesized for the first time by using two synthetic approaches. These synthetic materials allow for structural confirmation of COX metabolites of 8,9-EET and further study of their biological roles.

Indexed as

8,11,14-Eicosatrienoic AcidCyclooxygenase 2Molecular StructureStereoisomerism11-hydroxy-8,9-epoxyeicosatrienoic acid15-hydroxy-8,9-epoxyeicosatrienoic acid8,11,14-Eicosatrienoic Acid8,9-epoxyeicosatrienoic acidCyclooxygenase 2

Identifiers

PMID28470279
PMCPMC5527127
OpenAlexW2608648840

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.