ArticleThe Onderstepoort journal of veterinary research2017
The involvement of the hypothalamopituitary-adrenocortical axis in stress physiology and its significance in the assessment of animal welfare in cattle.
Article in The Onderstepoort journal of veterinary research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 50 citations in OpenAlex.
- Inferring associations among behavior, hormonal, neurotransmitter and IgA responses of dairy cows housed in automatic milking systems.Veterinary and animal science · 2026Article
- The Global Prevalence of Tuberculosis Infection in Buffaloes: A Systematic Review and Meta-Analysis.Animals : an open access journal from MDPI · 2026Review
- Livestock immunomodulators as alternatives to antimicrobials - a roadmap for the fight against drug resistance.BMC veterinary research · 2026Review
- Unfamiliar Handler-Induced Hypercortisolism, Abnormal Oral Behaviors, and Delayed Inflammatory Response in Pre-Weaned Zebu Cross Calves.Animals : an open access journal from MDPI · 2026Article
- Wolf Presence Disrupts Seasonal Variation in Hair Cortisol Among Free-Ranging Beef Cattle.Ecology and evolution · 2026Article
- Differential Expression of Hypothalamic Genes in Laying Hens Housed in Caged and Cage-Free Systems Under Commercial Conditions in the Tropics.Animals : an open access journal from MDPI · 2026Article
- Oxidative stress, serum metabolites, inflammatory cytokine changes associated with lumpy skin disease in cattle.BMC veterinary research · 2025Article
- Physical Measures of Welfare in Fin (Animals : an open access journal from MDPI · 2024Article
- Seasonal environmental fluctuations alter the transcriptome dynamics of oocytes and granulosa cells in beef cows.Journal of ovarian research · 2024Article
- Calf morbidity, mortality, and management practices in dairy farms in Jimma City, Southwestern Ethiopia.BMC veterinary research · 2023Article
- Stress amelioration potential of vitamin C in ruminants: a review.Tropical animal health and production · 2021Review
- Article
- Effects of Compost-Bedded Pack Barn on Circulating Cortisol and Beta-Endorphins in Dairy Cows: A Case Study.Animals : an open access journal from MDPI · 2021Article
- Melatonin-induced changes in the bovine vaginal microbiota during maternal nutrient restriction.Journal of animal science · 2021Article
- Effect of preshipment preconditioning and injectable antioxidant trace elements (Cu, Mn, Se, Zn) and vitamins (A, E) on plasma metabolite and hormone concentrations and growth in weaned beef cattle.Translational animal science · 2021Article
- The Effect of Stress on Reproduction and Reproductive Technologies in Beef Cattle-A Review.Animals : an open access journal from MDPI · 2020Review
- Interaction between stress hormones and phagocytic cells and its effect on the health status of dairy cows: A review.Veterinary world · 2020Review
- The Effect of Aerobic Physical Activity in Adrenaline Level in White Laboratory Rats.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2020Article
- Effects of transport stress on physiological responses and milk production in lactating dairy cows.Asian-Australasian journal of animal sciences · 2019Article
- An overview of the role of sympathetic regulation of immune responses in infectious disease and autoimmunity.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2018Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The intensification of cattle production has raised concern for animal welfare due to the stress that is associated with farming practices. The welfare of an animal is determined by the animal's ability to cope with or adapt to its continuously changing environment and the biological cost that is associated with this adaptation and maintenance. Stressors arise from various psychological, physiological and physical aspects of farming practices due to management and human-cattle interactions. Measuring the activity of the hypothalamopituitary-adrenocortical (HPA) axis with plasma cortisol levels is a useful method for determining the effects of stress on animals as it is stimulated at the onset of a perceived stress. The activation of the HPA axis affects various target tissues or systems and can result in suppression of the immune system, increased susceptibility to disease and adverse effects on reproductive success in prenatal and neonatal calves. Although some levels of stress associated with farming practices are unavoidable, improvements in farming methods need to be implemented in order to maintain or increase the efficiency of cattle production in a way that does not compromise the welfare of the animal.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.