Evidence map›Paper›PMID 28470003›Full record

ArticleFrontiers in veterinary science2017

Optimizing Fluorescein Isothiocyanate Dextran Measurement As a Biomarker in a 24-h Feed Restriction Model to Induce Gut Permeability in Broiler Chickens.

Mikayla F A Baxter, Ruben Merino-Guzman, Juan D Latorre, Brittany D Mahaffey, Yichao Yang, Kyle D Teague, Lucas E Graham, Amanda D Wolfenden, Xochitl Hernandez-Velasco, Lisa R Bielke and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 108 citations in OpenAlex.

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  17. Utilizing the apical-out enteroidsFrontiers in physiology · 2024
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Mikayla F A BaxterDepartment of Poultry Science, University of Arkansas, Fayetteville, AR, USA.
Ruben Merino-GuzmanFacultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Juan D LatorreDepartment of Poultry Science, University of Arkansas, Fayetteville, AR, USA.
Brittany D MahaffeyDepartment of Poultry Science, University of Arkansas, Fayetteville, AR, USA.
Yichao YangDepartment of Poultry Science, University of Arkansas, Fayetteville, AR, USA.
Kyle D TeagueDepartment of Poultry Science, University of Arkansas, Fayetteville, AR, USA.
Lucas E GrahamDepartment of Poultry Science, University of Arkansas, Fayetteville, AR, USA.
Amanda D WolfendenDepartment of Poultry Science, University of Arkansas, Fayetteville, AR, USA.
Xochitl Hernandez-VelascoFacultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Lisa R BielkeDepartment of Animal Science, The Ohio State University, Columbus, OH, USA.
Billy M HargisDepartment of Poultry Science, University of Arkansas, Fayetteville, AR, USA.
Guillermo TellezDepartment of Poultry Science, University of Arkansas, Fayetteville, AR, USA.
University of Arkansas at Fayetteville · USUniversidad Nacional Autónoma de México · MXThe Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluorescein isothiocyanate dextran (FITC-d) is a 3-5 kDa marker used to measure tight junction permeability. We have previously shown that intestinal barrier function can be adversely affected by stress, poorly digested diets, or feed restriction (FR), resulting in increased intestinal inflammation-associated permeability. However, further optimization adjustments of the current FITC-d methodology are possible to enhance precision and efficacy of results in future. The objective of the present study was to optimize our current model to obtain a larger difference between control and treated groups, by optimizing the FITC-d measurement as a biomarker in a 24-h FR model to induce gut permeability in broiler chickens. One

Indexed as

broiler chickensenteric inflammationfeed restrictionfluorescein isothiocyanate dextrangut permeability

Identifiers

PMID28470003
PMCPMC5396023
OpenAlexW2608874082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.