Evidence map›Paper›PMID 28469762›Full record

ArticleBiomicrofluidics2017

X-ray transparent microfluidic chips for high-throughput screening and optimization of

Jeremy M Schieferstein, Ashtamurthy S Pawate, Chang Sun, Frank Wan, Paige N Sheraden, Jana Broecker, Oliver P Ernst, Robert B Gennis, Paul J A Kenis

Open access · greenAbstract read
In one paragraph

Article in Biomicrofluidics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Jeremy M SchiefersteinDepartment of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Ashtamurthy S PawateDepartment of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Chang SunDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.ORCID 0000-0001-6070-5545
Frank WanDepartment of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Paige N SheradenDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Jana BroeckerDepartment of Biochemistry, University of Toronto, Toronto, Ontario M5S IA8, Canada.
Oliver P Ernst
Robert B GennisDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Paul J A KenisDepartment of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.ORCID 0000-0001-7348-0381
University of Illinois Urbana-Champaign · USUniversity of Toronto · CA

Funding

High-Speed High-Sensitivity Detector for X-ray Micro-Crystallography at GM/CA@APSS10OD012289 · OD · UNIVERSITY OF CHICAGO · PI FISCHETTI, ROBERT F. · 2014 to 2014
$2.0M
On-Chip Crystallization and In Situ X-ray Analysis of Membrane ProteinsR01GM086727 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI KENIS, PAUL J. A. · 2009 to 2011
$1.0M
NIGMS NIH HHS R01 GM086727NIH HHS S10 OD012289
6 · The paper itself

Abstract

Elucidating and clarifying the function of membrane proteins ultimately requires atomic resolution structures as determined most commonly by X-ray crystallography. Many high impact membrane protein structures have resulted from advanced techniques such as

Identifiers

PMID28469762
PMCPMC5403737
OpenAlexW2609156170

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.