ArticleFrontiers in aging neuroscience2017
Diminished Posterior Precuneus Connectivity with the Default Mode Network Differentiates Normal Aging from Alzheimer's Disease.
Article in Frontiers in aging neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
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Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Mapping cognitive deficits in cancer patients after chemotherapy: An Activation Likelihood Estimation meta-analysis of task-related fMRI studies.Brain imaging and behavior · 2022Pooled it
- Functional Neural Correlates of Anosognosia in Mild Cognitive Impairment and Alzheimer's Disease: a Systematic Review.Neuropsychology review · 2019Pooled it
- Bidirectional brain-heart interactions in health and disease.Nature reviews. Neurology · 2026Review
- Improving executive functioning and reducing the risk of Alzheimer's disease with music therapy: A narrative review of potential neural mechanisms.Journal of Alzheimer's disease : JAD · 2025Review
- Elevated vascular endothelial growth factor a is associated with disruption of default network connectivity in older adults.Brain imaging and behavior · 2025Article
- Physical activity andmedRxiv : the preprint server for health sciences · 2025Article
- Seeing through "brain fog": neuroimaging assessment and imaging biomarkers for cancer-related cognitive impairments.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Review
- Iron accumulation/overload and Alzheimer's disease risk factors in the precuneus region: A comprehensive narrative review.Aging medicine (Milton (N.S.W)) · 2024Review
- EEG signatures of cognitive decline after mild SARS-CoV-2 infection: an age-dependent study.BMC medicine · 2024Article
- Aging effects on the encoding/retrieval flip in associative memory: fMRI evidence from incidental contingency learning.Frontiers in aging neuroscience · 2024Article
- A metabolism-functional connectome sparse coupling method to reveal imaging markers for Alzheimer's disease based on simultaneous PET/MRI scans.Human brain mapping · 2023Article
- Functional gradients of the medial parietal cortex in a healthy cohort with family history of sporadic Alzheimer's disease.Alzheimer's research & therapy · 2023Article
- Genotypic effects of APOE-ε4 on resting-state connectivity in cognitively intact individuals support functional brain compensation.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- The effects of repetitive transcranial magnetic stimulation and aerobic exercise on cognition, balance and functional brain networks in patients with Alzheimer's disease.Cognitive neurodynamics · 2023Article
- Heart failure decouples the precuneus in interaction with social cognition and executive functions.Scientific reports · 2023Article
- Cerebral blood flow changes induced by high-frequency repetitive transcranial magnetic stimulation combined with cognitive training in Alzheimer's disease.Frontiers in neurology · 2023Article
- Brain dysconnectivity with heart failure.Brain communications · 2023Article
- Default mode network failure and neurodegeneration across aging and amnestic and dysexecutive Alzheimer's disease.Brain communications · 2023Article
- Changes in pairwise functional connectivity associated with changes in cognitive performance in cognitively normal older individuals: A two-year observational study.Neuroscience letters · 2022Observational
- Intravoxel incoherent motion diffusion-weighted imaging in the characterization of Alzheimer's disease.Brain imaging and behavior · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Both normal aging and Alzheimer's disease (AD) have been associated with a reduction in functional brain connectivity. It is unknown how connectivity patterns due to aging and AD compare. Here, we investigate functional brain connectivity in 12 young adults (mean age 22.8 ± 2.8), 12 older adults (mean age 73.1 ± 5.2) and 12 AD patients (mean age 74.0 ± 5.2; mean MMSE 22.3 ± 2.5). Participants were scanned during 6 different sessions with resting state functional magnetic resonance imaging (RS-fMRI), resulting in 72 scans per group. Voxelwise connectivity with 10 functional networks was compared between groups (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.