ArticleIndian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology
Profile of Primary Pediatric Brain and Spinal Cord Tumors from North India.
Article in Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 17 citations in OpenAlex.
- Spectrum of pediatric central nervous system tumors in North India: a histopathological and immunohistochemical study applying the WHO CNS 2021 classification.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Observational
- Primary Spinal Cord Tumors in Children: A Multi-institutional Retrospective Study from Pakistan.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- Review
- Neuroophthalmic Manifestations of Intracranial Tumours in Children.Case reports in ophthalmological medicine · 2021Article
- Preliminary study of central nervous system tumors' prevalence and incidence in Isfahan Province Iran.Journal of the Egyptian National Cancer Institute · 2020Article
- Histomorphological Spectrum of Pediatric Supratentorial CNS Tumors: A 3-year Retrospective Study in a Tertiary Care Center.Journal of pediatric neurosciencesArticle
- Pediatric Intracranial Tumors over a 5-Year Period in a Tertiary Care Center of North Kerala, India: A Retrospective Analysis.Asian journal of neurosurgeryArticle
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6 authors at 1 institution in 1 country.
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Abstract
BACKGROUND AND
objectiveThe study was carried out to find the profile of pediatric brain and spinal cord tumors during 2006-2015 in a tertiary referral center of North India. MATERIALS AND
methodsIt was a retrospective medical record-based observational study. All children <18 years of age with confirmed histopathological diagnosis of cancer were included in the study.
resultsCentral nervous system (CNS) tumors constituted 5.6% of all pediatric solid malignancies in our hospital. A total of 54 brain tumors and 13 spinal cord tumors were studied. Medulloblastoma was the most common brain tumor (20.3%) followed by pilocytic astrocytoma (16.6%) and glioblastoma multiforme (9.2%). The most common spinal cord tumor was Ewing's sarcoma/primitive neuroectodermal tumor (30.7%) followed by ependymoma (23%). Mean age was 10.5 years and 12.1 years for brain and spinal cord tumors, respectively. There was male predominance in brain tumors while the sex ratio was almost equal in spinal cord tumors. Histomorphologically, necrosis and angiogenesis were associated with higher grades of tumor. Approximately 35% children were alive after a mean follow-up of 36 ± 6 months.
conclusionCompared with most international studies, we found a higher percentage of medulloblastoma in the brain, thus stressing the role of regional and ethnic influences in the pathogenesis of CNS tumors.
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