ArticleScientific reports2017
Real-time intravascular photoacoustic-ultrasound imaging of lipid-laden plaque in human coronary artery at 16 frames per second.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
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Who cites it
53 citing papers in PubMed.
- In Vivo Microplastic Detection With Photoacoustic Imaging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- High-speed multimodal intravascular ultrasound and photoacoustic imaging system for atherosclerosis characterization.Biomedical optics express · 2026Article
- Precision percutaneous coronary intervention.NPJ cardiovascular health · 2026Review
- Compact photoacoustic endoscopy by measuring initial photoacoustic pressure using phase-shift interferometry.Photoacoustics · 2025Article
- What have we learnt from histology about the efficacy of coronary imaging modalities in assessing plaque composition?Frontiers in cardiovascular medicine · 2025Review
- Optical theranostics in ischemic heart disease: from molecular insights to clinical translation.Theranostics · 2025Review
- Enhanced dual-mode imaging: Superior photoacoustic and ultrasound endoscopy in live pigs using a transparent ultrasound transducer.Science advances · 2024Article
- Emerging Hybrid Intracoronary Imaging Technologies and Their Applications in Clinical Practice and Research.JACC. Cardiovascular interventions · 2024Review
- Recent Advances in Photoacoustic Imaging: Current Status and Future Perspectives.Micromachines · 2024Review
- Innovations in Intracoronary Imaging: Present Clinical Practices and Future Outlooks.Journal of clinical medicine · 2024Review
- Correction of high-rate motion for photoacoustic microscopy by orthogonal cross-correlation.Scientific reports · 2024Article
- Dual-modal Photoacoustic and Ultrasound Imaging: from preclinical to clinical applications.Frontiers in photonics · 2024Article
- Photoacoustic imaging on its way toward clinical utility: a tutorial review focusing on practical application in medicine.Journal of biomedical optics · 2023Review
- Supervised segmentation for guiding peripheral revascularization with forward-viewing, robotically steered ultrasound guidewire.Medical physics · 2023Article
- Longitudinal In Vivo Monitoring of Atheroprogression in Hypercholesterolemic Mice Using Photoacoustic Imaging.Thrombosis and haemostasis · 2023Article
- A high-sensitivity high-resolution intravascular photoacoustic catheter through mode cleaning in a graded-index fiber.Photoacoustics · 2023Article
- Diagnostics of atherosclerosis: Overview of the existing methods.Frontiers in cardiovascular medicine · 2023Review
- Optical-resolution functional gastrointestinal photoacoustic endoscopy based on optical heterodyne detection of ultrasound.Nature communications · 2022Article
- Survival intravascular photoacoustic imaging of lipid-rich plaque in cholesterol fed rabbits.Translational biophotonics · 2022Article
- Real-Time Detection and 3D Localization of Coronary Atherosclerosis Using a Microwave Imaging Technique: A Simulation Study.Sensors (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Intravascular photoacoustic-ultrasound (IVPA-US) imaging is an emerging hybrid modality for the detection of lipid-laden plaques, as it provides simultaneous morphological and lipid-specific chemical information of an artery wall. Real-time imaging and display at video-rate speed are critical for clinical utility of the IVPA-US imaging technology. Here, we demonstrate a portable IVPA-US system capable of imaging at up to 25 frames per second in real-time display mode. This unprecedented imaging speed was achieved by concurrent innovations in excitation laser source, rotary joint assembly, 1 mm IVPA-US catheter size, differentiated A-line strategy, and real-time image processing and display algorithms. Spatial resolution, chemical specificity, and capability for imaging highly dynamic objects were evaluated by phantoms to characterize system performance. An imaging speed of 16 frames per second was determined to be adequate to suppress motion artifacts from cardiac pulsation for in vivo applications. The translational capability of this system for the detection of lipid-laden plaques was validated by ex vivo imaging of an atherosclerotic human coronary artery at 16 frames per second, which showed strong correlation to gold-standard histopathology. Thus, this high-speed IVPA-US imaging system presents significant advances in the translational intravascular and other endoscopic applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.