Evidence map›Paper›PMID 28469173›Full record

Observational studyScientific reports2017

Correlates of insulin clearance in apparently healthy non-obese Japanese men.

Hideyoshi Kaga, Yoshifumi Tamura, Kageumi Takeno, Saori Kakehi, Takashi Funayama, Yasuhiko Furukawa, Miho Nishitani-Yokoyama, Kazunori Shimada, Hiroyuki Daida, Shigeki Aoki and 4 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

  1. Trial
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  4. Rationale and Design of the Study to Investigate the Metabolic Action of Imeglimin on Patients with Type 2 Diabetes Mellitus (SISIMAI).Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
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  9. Review
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  12. Targeting Insulin-Degrading Enzyme in Insulin Clearance.International journal of molecular sciences · 2021
    Review
  13. Observational
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Hideyoshi KagaDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Yoshifumi TamuraDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan. ys-tamur@juntendo.ac.jp.
Kageumi TakenoDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Saori KakehiDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Takashi FunayamaDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.ORCID 0000-0001-5405-9292
Yasuhiko FurukawaDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Miho Nishitani-YokoyamaDepartment of Cardiology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Kazunori ShimadaSportology Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Hiroyuki DaidaSportology Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Shigeki AokiSportology Center, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Adria GiaccaDepartments of Physiology and Medicine, Institute of Medical Science and Banting and Best Diabetes Centre, University of Toronto, Toronto, Canada.
Akio KanazawaDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.ORCID 0000-0003-2292-395X
Ryuzo KawamoriDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Hirotaka WatadaDepartment of Metabolism & Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Juntendo University · JPUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperinsulinemia observed in obese subject is caused at least in part by low metabolic clearance rate of insulin (MCRI). However, the determinants of MCRI in non-obese subjects are not fully understood. To investigate the correlates of MCRI in healthy non-obese men (BMI <25 kg/m

Indexed as

Adipose TissueAdultBlood GlucoseCholesterol, HDLCholesterol, LDLGlucose Clamp TechniqueHealthy VolunteersHumansHyperinsulinismInsulinInsulin ResistanceMaleMiddle AgedObesityProspective StudiesTriglyceridesBlood GlucoseCholesterol, HDLCholesterol, LDLInsulinTriglycerides

Identifiers

PMID28469173
PMCPMC5431197
OpenAlexW2608000885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.