ArticleScientific reports2017
Risk of infections in patients with gout: a population-based cohort study.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- A systematic review of the infectious complications of colchicine and the use of colchicine to treat infections.Seminars in arthritis and rheumatism · 2021Pooled it
- Evolutionary history of disease-susceptibility loci identified in longitudinal exome-wide association studies.Molecular genetics & genomic medicine · 2019Trial
- Risk factors for recurrent urinary tract infection after SGLT2 inhibitor reinitiation in type 2 diabetes.Endocrine · 2026Article
- The Outcomes of Patients With Hyperuricemia After Total Knee Arthroplasty: A Retrospective Cohort Study.Orthopaedic surgery · 2025Observational
- Comorbidities and their impact on in-hospital mortality in hospitalized adult patients with bacterial community-acquired pneumonia: a cohort study.Journal of thoracic disease · 2025Article
- Effect of gout on 30-day survival in ICU patients: retrospective analysis of a large cohort of critically ill patients.BMC rheumatology · 2025Article
- Downregulation of type I interferon signalling pathway by urate in primary human PBMCs.Immunology · 2025Article
- Total Hip Arthroplasty Outcomes in Patients with Gout: A Retrospective Analysis of Matched Large Cohorts.Clinics in orthopedic surgery · 2024Article
- Article
- Relationship between hyperuricemia with deposition and sexual dysfunction in males and females.Journal of endocrinological investigation · 2022Review
- Incident Gout: Risk of Death and Cause-Specific Mortality in Western Sweden: A Prospective, Controlled Inception Cohort Study.Frontiers in medicine · 2022Article
- Influenza vaccination and risk of atrial fibrillation in patients with gout: A nationwide population-based cohort study.Frontiers in pharmacology · 2022Article
- Drug-utilisation profiles and COVID-19.Scientific reports · 2021Article
- Obstructive sleep apnea and the risk of gout: a population-based case-control study.Arthritis research & therapy · 2020Article
- Asymptomatic hyperuricaemia: a silent activator of the innate immune system.Nature reviews. Rheumatology · 2020Review
- Cause-Specific Mortality in Gout: Novel Findings of Elevated Risk of Non-Cardiovascular-Related Deaths.Arthritis & rheumatology (Hoboken, N.J.) · 2019Article
- The accuracy of date of death recording in the Clinical Practice Research Datalink GOLD database in England compared with the Office for National Statistics death registrations.Pharmacoepidemiology and drug safety · 2019Article
- The Association Between Usage of Colchicine and Pneumonia: A Nationwide, Population-Based Cohort Study.Frontiers in pharmacology · 2019Article
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To investigate the risk of various types of infections (pneumonia and urinary tract infection (UTI)), and infection-related mortality in patients with gout compared with population-based controls. A retrospective cohort study was conducted using data from the UK Clinical Practice Research Datalink (CPRD). All patients with a first diagnosis of gout and aged >40 years between January 1987-July 2014, were included and matched with up to two controls. Time-varying Cox proportional hazards models were used to estimate the risk of infections and mortality. 131,565 patients and 252,763 controls (mean age: 64 years, 74% males, mean follow-up of 6.7 years) were included in the full cohort. After full statistical adjustment, the risk of pneumonia was increased (adj. HR 1.27, 95% CI 1.18 to 1.36), while the risk of UTI (adj. HR 0.99, 95% CI 0.97 to 1.01) was similar in patients compared to controls. No differences between patients and controls were observed for infection-related mortality due to pneumonia (adj. HR 1.03, 95% CI 0.93 to 1.14) or UTI (adj. HR 1.16, 95% CI 0.98 to 1.37). In conclusion, patients with gout did not have decreased risks of pneumonia, UTI or infection-related mortality compared to population-based controls.
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