Evidence map›Paper›PMID 28468910›Full record

ArticleGenetics2017

The SOS and RpoS Regulons Contribute to Bacterial Cell Robustness to Genotoxic Stress by Synergistically Regulating DNA Polymerase Pol II.

Tanja Dapa, Sébastien Fleurier, Marie-Florence Bredeche, Ivan Matic

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
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  3. Refining Viral Production Estimation.Environmental microbiology reports · 2025
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  8. Insights into antibiotic resistance promoted by quinolone exposure.Antimicrobial agents and chemotherapy · 2025
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  12. Article
  13. Article
  14. Article
  15. Article
  16. Rcs phosphorelay affects the sensitivity ofFrontiers in microbiology · 2022
    Article
  17. Article
  18. Article
  19. A Comprehensive View of Translesion Synthesis in Escherichia coli.Microbiology and molecular biology reviews : MMBR · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Tanja DapaINSERM U1001, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine Paris Descartes, 75014, France.
Sébastien FleurierINSERM U1001, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine Paris Descartes, 75014, France.
Marie-Florence BredecheINSERM U1001, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine Paris Descartes, 75014, France.
Ivan MaticINSERM U1001, Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine Paris Descartes, 75014, France ivan.matic@inserm.fr.
Inserm · FRCentre National de la Recherche Scientifique · FRSorbonne Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitomycin C (MMC) is a genotoxic agent that induces DNA cross-links, DNA alkylation, and the production of reactive oxygen species (ROS). MMC induces the SOS response and RpoS regulons in

Indexed as

DNA DamageSOS Response, GeneticsAnti-Bacterial AgentsBacterial ProteinsEscherichia coliEscherichia coli ProteinsMitomycinMutagensReactive Oxygen SpeciesRegulonSigma FactorAnti-Bacterial AgentsBacterial ProteinsEscherichia coli ProteinsMitomycinMutagenspolB protein, E coliReactive Oxygen SpeciesSigma Factorsigma factor KatF protein, BacteriaDNA polymerase IIEscherichia colimitomycin CRpoSSOS

Identifiers

PMID28468910
PMCPMC5500135
OpenAlexW2610211277

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.