Evidence map›Paper›PMID 28468886›Full record

ArticleJournal of virology2017

Human Sera Collected between 1979 and 2010 Possess Blocking-Antibody Titers to Pandemic GII.4 Noroviruses Isolated over Three Decades.

Sumit Sharma, Beatrice Carlsson, Rita Czakó, Sirkka Vene, Mats Haglund, Johnny Ludvigsson, Göran Larson, Lennart Hammarström, Stanislav V Sosnovtsev, Robert L Atmar and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Sumit SharmaDivision of Molecular Virology, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Beatrice CarlssonDivision of Molecular Virology, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
Rita CzakóDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Sirkka VenePublic Health Agency of Sweden, Stockholm, Sweden.
Mats HaglundDepartment of Infectious Diseases, County Hospital Kalmar, Kalmar, Sweden.
Johnny LudvigssonDivision of Pediatrics and Diabetes Research Centre, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden.
Göran LarsonDepartment of Clinical Chemistry and Transfusion Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Lennart HammarströmDepartment of Laboratory Medicine, Division of Clinical Immunology and Transfusion Medicine, Karolinska Institute, Stockholm, Sweden.
Stanislav V SosnovtsevLaboratory of Infectious Diseases, NIAID, National Institutes of Health, Bethesda, Maryland, USA.
Robert L AtmarDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Kim Y GreenLaboratory of Infectious Diseases, NIAID, National Institutes of Health, Bethesda, Maryland, USA.
Mary K EstesDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Lennart SvenssonDivision of Molecular Virology, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden lennart.t.svensson@liu.se.
Baylor College of Medicine · USLinköping University · SEKarolinska Institutet · SENational Institute of Allergy and Infectious Diseases · USLandstinget i Kalmar län · SEPublic Health Agency of Sweden · SEUniversity of Gothenburg · SE

Funding

X-ray Crystallographic Studies on CalicivirusesP01AI057788 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI ATMAR, ROBERT L., ESTES, MARY KOLB · 2004 to 2024
$34.4M
Noroviruses and Epidemic GastroenteritisZIAAI000897 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI GREEN, KIM Y. · 2009 to 2025
$29.6M
NIAID NIH HHS P01 AI057788
6 · The paper itself

Abstract

The emergence of pandemic GII.4 norovirus (NoV) strains has been proposed to occur due to changes in receptor usage and thereby to lead to immune evasion. To address this hypothesis, we measured the ability of human sera collected between 1979 and 2010 to block glycan binding of four pandemic GII.4 noroviruses isolated in the last 4 decades. In total, 268 sera were investigated for 50% blocking titer (BT

Indexed as

Virus AttachmentAdultAgedAntibodies, BlockingCaliciviridae InfectionsGenotypeHumansMiddle AgedMucinsNorovirusAntibodies, BlockingMucinsnoroviruspandemicVLP

Identifiers

PMID28468886
PMCPMC5487561
OpenAlexW2611446875

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.