ArticleJournal of virology2017
Cell Culture Systems To Study Human Herpesvirus 6A/B Chromosomal Integration.
Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 38 citations in OpenAlex.
- A Patient-Derived iPSC-Based Model Reveals Neural Lineage-Specific Transcription of Endogenous HHV-6B.The Journal of infectious diseases · 2026Article
- Human herpesvirus 7 integrates into host telomeres via its telomeric repeat arrays.PLoS pathogens · 2026Article
- New Assay Systems to Characterize the Broad-Spectrum Antiherpesviral and Non-Herpesviral Activity of Cyclin-Dependent Kinase (CDK) 8 Inhibitors.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Identification of stimuli that enhance human herpesvirus 6A (HHV-6A) replication and reconstitution.Journal of virology · 2024Article
- The immediate-early protein 1 of human herpesvirus 6B interacts with NBS1 and inhibits ATM signaling.EMBO reports · 2024Article
- Transmission dynamics of human herpesvirus 6A, 6B and 7 from whole genome sequences of families.Virology journal · 2022Article
- Expression of the human herpesvirus 6A latency-associated transcript U94A impairs cytoskeletal functions in human neural cells.Molecular and cellular neurosciences · 2022Article
- Impact of Host Telomere Length on HHV-6 Integration.Viruses · 2022Article
- Article
- Mapping the Human Herpesvirus 6B transcriptome.Journal of virology · 2021Article
- Higher-Order Chromatin Structures of Chromosomally Integrated HHV-6A Predict Integration Sites.Frontiers in cellular and infection microbiology · 2021Article
- The Promyelocytic Leukemia Protein facilitates human herpesvirus 6B chromosomal integration, immediate-early 1 protein multiSUMOylation and its localization at telomeres.PLoS pathogens · 2020Article
- Role for the shelterin protein TRF2 in human herpesvirus 6A/B chromosomal integration.PLoS pathogens · 2020Article
- Inherited Chromosomally Integrated Human Herpesvirus 6 Demonstrates Tissue-Specific RNA ExpressionJournal of virology · 2019Article
- Review
- A complex evolutionary relationship between HHV-6A and HHV-6B.Virus evolution · 2019Article
- Chromatin Profiles of Chromosomally Integrated Human Herpesvirus-6A.Frontiers in microbiology · 2019Article
- Viral Proteins U41 and U70 of Human Herpesvirus 6A Are Dispensable for Telomere Integration.Viruses · 2018Article
- Screening for 15 pathogenic viruses in human cell lines registered at the JCRB Cell Bank: characterization ofRoyal Society open science · 2018Article
- HHV-6 encoded small non-coding RNAs define an intermediate and early stage in viral reactivation.NPJ genomic medicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 4 countries.
Funding
Abstract
Human herpesviruses 6A/B (HHV-6A/B) can integrate their viral genomes in the telomeres of human chromosomes. The viral and cellular factors contributing to HHV-6A/B integration remain largely unknown, mostly due to the lack of efficient and reproducible cell culture models to study HHV-6A/B integration. In this study, we characterized the HHV-6A/B integration efficiencies in several human cell lines using two different approaches. First, after a short-term infection (5 h), cells were processed for single-cell cloning and analyzed for chromosomally integrated HHV-6A/B (ciHHV-6A/B). Second, cells were infected with HHV-6A/B and allowed to grow in bulk for 4 weeks or longer and then analyzed for the presence of ciHHV-6. Using quantitative PCR (qPCR), droplet digital PCR, and fluorescent
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.