ArticleBMC psychiatry2017
Personality traits in bipolar disorder and influence on outcome.
Article in BMC psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Five-factor personality traits in patients with schizophrenia and bipolar disorder: a systematic review and meta-analysis.The international journal of neuropsychopharmacology · 2025Pooled it
- Antisocial Personality Disorder in Bipolar Disorder: A Systematic Review.Medicina (Kaunas, Lithuania) · 2021Pooled it
- The Inaccuracy of the Mood Disorder Questionnaire for Bipolar Disorder in a Community Sample: From the "DYMERS" Construct Toward a New Instrument for Detecting Vulnerable Conditions.Journal of clinical medicine · 2025Article
- Temperament and character traits and profiles: impact on bipolar disorder risk and onset age.Frontiers in psychiatry · 2025Article
- The St. Göran Project: A Multipronged Strategy for Longitudinal Studies for Bipolar Disorders.Neuropsychobiology · 2025Article
- Personality functioning in bipolar 1 disorder and borderline personality disorder.BMC psychiatry · 2024Article
- Comparative Analysis of Personality Traits in Major Depressive Disorder and Bipolar Disorder: Impact, Differences, and Associations with Symptoms.Neuropsychiatric disease and treatment · 2024Article
- Temperament traits mediate the relationship between CACNA1C polymorphisms and bipolar disorder in cisgender women.European archives of psychiatry and clinical neuroscience · 2023Article
- Psychometric property study of the Affective Lability Scale-short form in Chinese patients with mood disorders.Frontiers in psychiatry · 2023Article
- Investigating the phenotypic and genetic associations between personality traits and suicidal behavior across major mental health diagnoses.European archives of psychiatry and clinical neuroscience · 2022Article
- Pharmacotherapy of Disruptive Behaviors in Children with Intellectual Disabilities.Paediatric drugs · 2022Review
- Strategies and foundations for scientific discovery in longitudinal studies of bipolar disorder.Bipolar disorders · 2022Review
- Article
- The big five model in bipolar disorder: a latent profile analysis and its impact on longterm illness severity.International journal of bipolar disorders · 2022Article
- Clinical Impact of Psychopathy on Bipolar Disorder.Medicina (Kaunas, Lithuania) · 2021Article
- Preclinical Considerations about Affective Disorders and Pain: A Broadly Intertwined, yet Often Under-Explored, Relationship Having Major Clinical Implications.Medicina (Kaunas, Lithuania) · 2020Review
- Personality and the Expression of Symptomatology in Schizophrenia and Bipolar Disorder.The Journal of nervous and mental disease · 2019Article
- Leveraging brain cortex-derived molecular data to elucidate epigenetic and transcriptomic drivers of complex traits and disease.Translational psychiatry · 2019Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim was to investigate the personality profile of bipolar disorder I and II, and healthy controls, and to study whether personality influences the course of bipolar disorder.
methodsOne hundred ten patients with bipolar disorder I, 85 patients with bipolar disorder II, and 86 healthy individuals had their personality profile assessed using the Swedish universities Scales of Personality (SSP), an instrument developed to explore personality-related vulnerabilities and correlates of psychiatric disorders. Patients were followed prospectively for 2 years. To assess the impact of Neuroticism, Aggressiveness, and Disinhibition on illness course, we performed logistic regressions with the outcome variables mood episodes (depressive, hypo/manic, mixed), suicide attempts, violence, and the number of sick leave days.
resultsBipolar disorder I and II demonstrated higher global measures of Neuroticism, Aggressiveness, and Disinhibition as compared with healthy controls. A third of the patients scored ≥1 SD above the population-based normative mean on the global neuroticism measure. The two subtypes of bipolar disorder were, however, undistinguishable on all of the personality traits. In the unadjusted model, higher neuroticism at baseline predicted future depressive episodes and suicide attempts/violent behavior, but this association disappeared when adjusting for baseline depressive symptoms as assessed with MADRS.
conclusionsA significant minority of the patients scored ≥1 SD above the population mean on the global measures of Neuroticism, Aggressiveness and Disinhibition; scores this high are usually evident clinically. Yet, the personality profile does not seem to have prognostic value over a 2-year period.
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