ArticleCritical care (London, England)2017
Blood pressure deficits in acute kidney injury: not all about the mean arterial pressure?
Article in Critical care (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- The relationship between intraoperative hypotension and acute kidney injury in elderly and super elderly patients undergoing noncardiac surgery: a retrospective cohort analysis.BMC geriatrics · 2025Article
- Effect of intraoperative hypotension depth and duration on acute kidney injury after Type A acute aortic dissection repair: An observational cohort study based on early risk stratification models.Journal of anesthesia and translational medicine · 2025Article
- Associations of Genetic Variations in the NR3C2 With Salt Sensitivity, Longitudinal Blood Pressure Changes, and Incidence of Hypertension in Chinese Adults.Journal of clinical hypertension (Greenwich, Conn.) · 2025Observational
- The Furosemide Stress Test: A Dynamic Tool for Predicting Acute Kidney Injury Progression in Critical Care Medicine.Journal of clinical medicine · 2025Review
- A dynamic model to predict early occurrence of acute kidney injury in ICU hospitalized cirrhotic patients: a MIMIC database analysis.BMC gastroenterology · 2024Article
- Associations of systolic blood pressure and in-hospital mortality in critically ill patients with acute kidney injury.International urology and nephrology · 2023Article
- Traumatic injuries to the renal blood vessels and in-hospital renal complications in patients with penetrating or blunt trauma.Frontiers in surgery · 2023Article
- Incorporating intraoperative blood pressure time-series variables to assist in prediction of acute kidney injury after type a acute aortic dissection repair: an interpretable machine learning model.Annals of medicine · 2023Article
- The blood pressure targets in sepsis patients with acute kidney injury: An observational cohort study of multiple ICUs.Frontiers in immunology · 2022Observational
- The effect of targeting Tie2 on hemorrhagic shock-induced renal perfusion disturbances in rats.Intensive care medicine experimental · 2021Article
- Perioperative risk factors associated with delayed graft function following deceased donor kidney transplantation: A retrospective, single center study.World journal of transplantation · 2021Article
- Indwelling catheters increase altered mental status and urinary tract infection risk: A retrospective Cohort Study.Annals of medicine and surgery (2012) · 2021Article
- The Association Between Obesity and Risk of Acute Kidney Injury After Cardiac Surgery.Frontiers in endocrinology · 2020Article
- Optimal systolic blood pressure in noncritically ill patients with acute kidney injury: A retrospective cohort study.Kidney research and clinical practice · 2019Article
- Associations between tricuspid annular plane systolic excursion to reflect right ventricular function and acute kidney injury in critically ill patients: a SICS-I sub-study.Annals of intensive care · 2019Article
- Kidney histopathology in lethal human sepsis.Critical care (London, England) · 2018Article
- [Prevention of acute kidney injury in critically ill patients : Recommendations from the renal section of the DGIIN, ÖGIAIN and DIVI].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute kidney injury (AKI) is associated with increased morbidity and mortality. Although there are many causes of AKI, it is known that patients undergoing high-risk surgery are known to be at significant risk. Although much effort has centred on the minimum arterial pressure needed to maintain renal perfusion, this tends to be based on relatively crude measures such as the mean arterial pressure (MAP), which is widely used as an index for the optimal blood pressure. The rationale behind maintaining MAP is to provide adequate organ perfusion, although this is difficult to assess other than by applying crude end-points. Recent studies have examined the progression of AKI as defined by the KDIGO criteria in terms of time-weighted average values for premorbid and within-ICU haemodynamic pressure-related parameters. Although principally performed on patients who had undergone cardiovascular surgery and who were on vasopressor support, some interesting results were obtained suggesting that crude MAP may not be an adequate target in AKI. In patients with AKI progression, greater observed deficits in mean perfusion pressure, diastolic arterial perfusion, and diastolic perfusion pressures were observed. This study may highlight potential modifiable risk factors for the prevention of progression of AKI, and hopefully translate into improved outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.