Evidence map›Paper›PMID 28468303›Full record

ArticleNutrients2017

Association between Alcohol Consumption, Folate Intake, and Risk of Pancreatic Cancer: A Case-Control Study.

Winta Yallew, William R Bamlet, Ann L Oberg, Kristin E Anderson, Janet E Olson, Rashmi Sinha, Gloria M Petersen, Rachael Z Stolzenberg-Solomon, Rick J Jansen

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Winta Yallew
William R BamletDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA. Bamlet.William4@mayo.edu.
Ann L ObergDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA. Oberg.Ann@mayo.edu.
Kristin E AndersonDepartment of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55455, USA. ander116@umn.edu.
Janet E OlsonDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA. Olson.Janet@mayo.edu.
Rashmi SinhaDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20850, USA. sinhar@mail.nih.gov.
Gloria M PetersenDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA. Petersen.Gloria@mayo.edu.
Rachael Z Stolzenberg-SolomonDepartment of Epidemiology, National Institutes of Health, Bethesda, MD 20850, USA. Rachael.Solomon@nih.gov.
Rick J JansenDepartment of Public Health, North Dakota State University, Fargo, ND 58102, USA. rick.jansen@ndsu.edu.
Mayo Clinic in Florida · USNorth Dakota State University · USNational Cancer Institute · USNational Institutes of Health · USUniversity of Minnesota · US

Funding

Tissue CoreP50CA102701 · NCI · MAYO CLINIC ROCHESTER · PI PETERSEN, GLORIA M. · 2004 to 2018
$32.7M
Mayo Cancer Genetic Epidemiology Training ProgramR25CA092049 · NCI · MAYO CLINIC ROCHESTER · PI PETERSEN, GLORIA M., VACHON, CELINE M · 2001 to 2018
$5.3M
NCI NIH HHS P50 CA102701NCI NIH HHS R25 CA092049
6 · The paper itself

Abstract

Pancreatic cancer is one of the most fatal common cancers affecting both men and women, representing about 3% of all new cancer cases in the United States. In this study, we aimed to investigate the association of pancreatic cancer risk with alcohol consumption as well as folate intake. We performed a case-control study of 384 patients diagnosed with pancreatic cancer from May 2004 to December 2009 and 983 primary care healthy controls in a largely white population (>96%). Our findings showed no significant association between risk of pancreatic cancer and either overall alcohol consumption or type of alcohol consumed (drinks/day). Our study showed dietary folate intake had a modest effect size, but was significantly inversely associated with pancreatic cancer (odds ratio (OR) = 0.99, p < 0.0001). The current study supports the hypothesis that pancreatic cancer risk is reduced with higher food-based folate intake.

Indexed as

DietAgedAlcohol DrinkingBody Mass IndexCase-Control StudiesDietary SupplementsFemaleFolic AcidHumansMaleMiddle AgedNutritional StatusPancreatic NeoplasmsRisk FactorsFolic Acidalcohol intakecase-control studyfolate intakepancreatic cancer

Identifiers

PMID28468303
PMCPMC5452178
OpenAlexW2609622432

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.