Evidence map›Paper›PMID 28468286›Full record

ArticleInternational journal of molecular sciences2017

Clinical Utility of the Adrenocorticotropin Stimulation Test with/without Dexamethasone Suppression for Definitive and Subtype Diagnosis of Primary Aldosteronism.

Kosuke Inoue, Masao Omura, Chiho Sugisawa, Yuya Tsurutani, Jun Saito, Tetsuo Nishikawa

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. [Comparison of Different Doses of ACTH Used in ACTH Stimulation Test to Determine the Subtypes of Primary Aldosteronism].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Observational
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kosuke InoueEndocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama 222-0036, Japan. koinoue-tky@umin.ac.jp.
Masao OmuraEndocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama 222-0036, Japan. omura@yokohamah.johas.go.jp.
Chiho SugisawaEndocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama 222-0036, Japan. pochi_dog103@yahoo.co.jp.
Yuya TsurutaniEndocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama 222-0036, Japan. yuya97tsuru1055@gmail.com.
Jun SaitoEndocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama 222-0036, Japan. saitoj@yokohamah.johas.go.jp.
Tetsuo NishikawaEndocrinology and Diabetes Center, Yokohama Rosai Hospital, Yokohama 222-0036, Japan. tetsuon@yokohamah.johas.go.jp.
Yokohama Rosai Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The adrenocorticotropin (ACTH) stimulation test (AST) has been reported to be useful for diagnosing primary aldosteronism (PA), particularly for differentiating PA subtypes under 1-mg dexamethasone suppression (DS). The aim of our study was to clarify the effect of 1-mg DS on AST results. A retrospective cohort study was conducted using data for 48 patients (PA: 30/48). We estimated the difference in plasma aldosterone concentration (PAC) responsiveness to ACTH stimulation with single (AST alone) and combined (AST under 1-mg DS) tests within the same patient. We compared the diagnostic accuracy of these two tests for PA and the laterality of hyperaldosteronism. We found no differences in PAC responsiveness to ACTH stimulation between single and combined tests, and observed a significant positive linear relationship (30 min,

Indexed as

Adrenal Cortex Function TestsAdrenocorticotropic HormoneAdultAldosteroneDexamethasoneFemaleHumansHyperaldosteronismMaleMiddle AgedAdrenocorticotropic HormoneAldosteroneDexamethasoneadrenocorticotropin (ACTH) stimulation testdexamethasone suppression testprimary aldosteronism

Identifiers

PMID28468286
PMCPMC5454861
OpenAlexW2611136454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.