Evidence map›Paper›PMID 28468279›Full record

ArticleInternational journal of molecular sciences2017

Applying Unconventional Secretion in Ustilago maydis for the Export of Functional Nanobodies.

Marius Terfrüchte, Michèle Reindl, Silke Jankowski, Parveen Sarkari, Michael Feldbrügge, Kerstin Schipper

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Expression and Detection of Heterologous Proteins in Ustilago maydis.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  3. Review
  4. Article
  5. EngineeringMetabolic engineering communications · 2021
    Article
  6. Article
  7. A Novel Potent Carrier for Unconventional Protein Export inFrontiers in cell and developmental biology · 2021
    Article
  8. Article
  9. Article
  10. Review
  11. A Potential Lock-Type Mechanism for Unconventional Secretion in Fungi.International journal of molecular sciences · 2019
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Marius TerfrüchteInstitute for Microbiology, Cluster for Excellence on Plant Sciences, Heinrich Heine University Düsseldorf, 40204 Düsseldorf, Germany. marius.terfruechte@hhu.de.
Michèle ReindlInstitute for Microbiology, Cluster for Excellence on Plant Sciences, Heinrich Heine University Düsseldorf, 40204 Düsseldorf, Germany. michele.reindl@hhu.de.
Silke JankowskiInstitute for Microbiology, Cluster for Excellence on Plant Sciences, Heinrich Heine University Düsseldorf, 40204 Düsseldorf, Germany. silke.jankowski@hhu.de.
Parveen SarkariDepartment of Biotechnology (DBT), Muthgasse 18, 1190 Vienna, Austria. parveen.sarkari@boku.ac.at.
Michael FeldbrüggeInstitute for Microbiology, Cluster for Excellence on Plant Sciences, Heinrich Heine University Düsseldorf, 40204 Düsseldorf, Germany. feldbrue@hhu.de.
Kerstin SchipperInstitute for Microbiology, Cluster for Excellence on Plant Sciences, Heinrich Heine University Düsseldorf, 40204 Düsseldorf, Germany. kerstin.schipper@uni-duesseldorf.de.
Forschungszentrum Jülich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exploiting secretory pathways for production of heterologous proteins is highly advantageous with respect to efficient downstream processing. In eukaryotic systems the vast majority of heterologous proteins for biotechnological application is exported via the canonical endoplasmic reticulum-Golgi pathway. In the endomembrane system target proteins are often glycosylated and may thus be modified with foreign glycan patterns. This can be destructive for their activity or cause immune reactions against therapeutic proteins. Hence, using unconventional secretion for protein expression is an attractive alternative. In the fungal model

Indexed as

Botulinum Toxins, Type AChitinChitinasesCloning, MolecularFungal ProteinsGreen Fluorescent ProteinsIndustrial MicrobiologyProtein TransportRecombinant ProteinsSingle-Domain AntibodiesUstilagoBotulinum Toxins, Type AChitinChitinasesFungal ProteinsGreen Fluorescent ProteinsRecombinant ProteinsSingle-Domain Antibodiesbotulinum toxin Achitinasenanobodyunconventional secretionUstilago maydis

Identifiers

PMID28468279
PMCPMC5454850
OpenAlexW2610213448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.