Evidence map›Paper›PMID 28467887›Full record

ReviewMechanisms of development2017

Cadherins function during the collective cell migration of Xenopus Cranial Neural Crest cells: revisiting the role of E-cadherin.

Hélène Cousin

Open access · greenAbstract readReview
In one paragraph

Review in Mechanisms of development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Hélène CousinDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, United States. Electronic address: hcousin@vasci.umass.edu.
University of Massachusetts Amherst · US

Funding

Role of Lbh during craniofacial development of vertebratesR03DE025692 · NIDCR · UNIVERSITY OF MASSACHUSETTS AMHERST · PI COUSIN, HELENE · 2016 to 2017
$227k
NIDCR NIH HHS R03 DE025692
6 · The paper itself

Abstract

Collective cell migration is a process whereby cells move while keeping contact with other cells. The Xenopus Cranial Neural Crest (CNC) is a population of cells that emerge during early embryogenesis and undergo extensive migration from the dorsal to ventral part of the embryo's head. These cells migrate collectively and require cadherin mediated cell-cell contact. In this review, we will describe the key features of Xenopus CNC migration including the key molecules driving their migration. We will also review the role of the various cadherins during Xenopus CNC emergence and migration. Lastly, we will discuss the recent and seemingly controversial findings showing that E-cadherin presence is essential for CNC migration.

Indexed as

AnimalsCadherinsCell AdhesionCell MovementGene Expression Regulation, DevelopmentalNeural CrestSkullXenopusCadherinsCadherinCollective migrationCranial neural crestEMTXenopus

Identifiers

PMID28467887
PMCPMC5662486
OpenAlexW2609172188

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.