Evidence map›Paper›PMID 28467794›Full record

SynthesisOncotarget2017

Long non-coding RNAs in renal cell carcinoma: A systematic review and clinical implications.

Ming Li, Ying Wang, Liang Cheng, Wanting Niu, Guoan Zhao, Jithin K Raju, Jun Huo, Bin Wu, Bo Yin, Yongsheng Song and 1 more

Open access · diamondAbstract readSystematic Review
In one paragraph

Synthesis in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
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  12. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Ming LiDepartment of Urology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China.
Ying WangDepartment of Nuclear Medicine, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China.
Liang ChengDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Wanting NiuDepartment of Orthopedics, Brigham and Women's Hospital, VA Boston Healthcare System, Harvard Medical School, Boston, Massachusetts 02115, USA.
Guoan ZhaoSchool of Network Education, Beijing University of Posts and Telecommunications, Hebei, Beijing 100088, P.R. China.
Jithin K RajuDepartment of Clinical Medicine, China Medical University, Shenyang, Liaoning 110122, P.R. China.
Jun HuoDepartment of Urology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China.
Bin WuDepartment of Urology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China.
Bo YinDepartment of Urology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China.
Yongsheng SongDepartment of Urology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China.
Renge BuDepartment of Urology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China.
China Medical University · CNBeijing University of Posts and Telecommunications · CNHarvard University · USIndiana University School of MedicineVA Boston Healthcare System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal cell carcinoma is one of the most common malignancy in adults, its prognosis is poor in an advanced stage and early detection is difficult due to the lack of molecular biomarkers. The identification of novel biomarkers for RCC is an urgent and meaningful project. Long non-coding RNA (lncRNA) is transcribed from genomic regions with a minimum length of 200 bases and limited protein-coding potential. Recently, lncRNAs have been greatly studied in a variety of cancer types. They participate in a wide variety of biological processes including cancer biology. In this review, we provide a new insight of the profiling of lncRNAs in RCC and their roles in renal carcinogenesis, with an emphasize on their potential in diagnosis, prognosis and potential roles in RCC therapy.

Indexed as

Gene Expression Regulation, NeoplasticBiomarkers, TumorCarcinoma, Renal CellCell Transformation, NeoplasticHumansKidney NeoplasmsNeoplasm GradingNeoplasm MetastasisNeoplasm StagingPrognosisRNA, Long NoncodingBiomarkers, TumorRNA, Long NoncodingdiagnosislncRNAprognosisrenal cell carcinomatherapy

Identifiers

PMID28467794
PMCPMC5564659
OpenAlexW2606766181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.