Evidence map›Paper›PMID 28467726›Full record

ArticleAIDS research and human retroviruses2017

Short Communication: HIV Patient Systemic Mitochondrial Respiration Improves with Exercise.

Morgan Kocher, Mindy McDermott, Rachel Lindsey, Cecilia M Shikuma, Mariana Gerschenson, Dominic C Chow, Lindsay B Kohorn, Ronald K Hetzler, Iris F Kimura

Open access · greenAbstract read
In one paragraph

Article in AIDS research and human retroviruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Morgan Kocher1 Department of Kinesiology and Rehabilitation Science, College of Education, University of Hawaii at Manoa , Honolulu, Hawaii.
Mindy McDermott2 Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii at Manoa , Honolulu, Hawaii.
Rachel Lindsey1 Department of Kinesiology and Rehabilitation Science, College of Education, University of Hawaii at Manoa , Honolulu, Hawaii.
Cecilia M Shikuma3 Department of Medicine, Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawaii at Manoa , Honolulu, Hawaii.
Mariana Gerschenson2 Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii at Manoa , Honolulu, Hawaii.
Dominic C Chow3 Department of Medicine, Hawaii Center for AIDS, John A. Burns School of Medicine, University of Hawaii at Manoa , Honolulu, Hawaii.
Lindsay B Kohorn2 Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii at Manoa , Honolulu, Hawaii.
Ronald K Hetzler1 Department of Kinesiology and Rehabilitation Science, College of Education, University of Hawaii at Manoa , Honolulu, Hawaii.
Iris F Kimura1 Department of Kinesiology and Rehabilitation Science, College of Education, University of Hawaii at Manoa , Honolulu, Hawaii.
University of Hawaiʻi at Mānoa · US

Funding

TRPA1 Physiology in Diabetes, Metabolic Syndrome, and MetabolismP20GM113134 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI Kathryn Jaques Schunke · 2017 to 2026
$21.5M
RESEARCH DESIGN AND BIOSTATISTICS COREU54MD007584 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI MOKUAU, NOREEN, SHIRAMIZU, BRUCE T · 2012 to 2018
$21.1M
NIGMS NIH HHS P20 GM113134NIMHD NIH HHS U54 MD007584
6 · The paper itself

Abstract

In HIV-infected individuals, impaired mitochondrial function may contribute to cardiometabolic disease as well as to fatigue and frailty. Aerobic exercise improves total body energy reserves; however, its impact at the cellular level is unknown. We assessed alterations in cellular bioenergetics in peripheral blood mononuclear cells (PBMC) before and after a 12-week aerobic exercise study in sedentary HIV-infected subjects on stable antiretroviral therapy who successfully completed a 12-week aerobic exercise program. In this prospective study, participants underwent supervised 20-40 min of light aerobic exercise (walking or jogging) performed three times per week for 12 weeks, gradually increasing to maintain an intensity of 50%-80% of heart rate reserve. Maximal aerobic capacity (VO

Indexed as

Cell RespirationEnergy MetabolismExerciseHeart RateHIV InfectionsHumansMitochondriaOxygen ConsumptionPatient CompliancePhysical FitnessPilot ProjectsProspective StudiesTime Factorsaerobiccardiovascular fitnessVO2MAX

Identifiers

PMID28467726
PMCPMC5650718
OpenAlexW2765247103

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.