ArticlePloS one2017
Effect of dialysis modality on frailty phenotype, disability, and health-related quality of life in maintenance dialysis patients.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 4 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Association Between Frailty and Mortality, Falls and Hospitalisation Among Patients Undergoing Dialysis: A Systematic Review and Meta-Analysis.Nursing open · 2025Pooled it
- Global prevalence of frailty in hemodialysis patients: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Oral health-related quality of life in adult patients with end-stage kidney diseases undergoing renal replacement therapy - a systematic review.BMC nephrology · 2020Pooled it
- The prevalence of frailty in patients on hemodialysis: a systematic review and meta-analysis.International urology and nephrology · 2020Pooled it
- Health-related quality of life in patients on maintenance hemodialysis: Evidence from southern Iran using EQ-5D-5L and KDQOL-SF.PloS one · 2026Article
- Frailty Assessment Tools in Chronic Kidney Disease: A Systematic Review and Meta-analysis.Kidney medicine · 2025Article
- Self-efficacy, social support and oral health-related quality of life in patients with kidney transplantation and under hemodialysis.BMC nephrology · 2024Article
- Mortality and disability-adjusted life years in North Africa and Middle East attributed to kidney dysfunction: a systematic analysis for the Global Burden of Disease Study 2019.Clinical kidney journal · 2024Article
- Association between disability in activities of daily living and phase angle in hemodialysis patients.BMC nephrology · 2023Observational
- Quality of Life among Peritoneal and Hemodialysis Patients: A Cross-Sectional Study.Clinics and practice · 2023Article
- Frailty in Older Patients Undergoing Hemodialysis and Its Association with All-Cause Mortality: A Prospective Cohort Study.Clinical interventions in aging · 2022Observational
- Health-related quality of life associated with risk of death in Brazilian dialysis patients: an eight-year cohort.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Observational
- Bridging the gap from research to practice for enhanced health-related quality of life in people with chronic kidney disease.Clinical kidney journal · 2021Review
- The relationship between disability and clinical outcomes in maintenance dialysis patients.Yeungnam University journal of medicine · 2021Article
- An overview of frailty in kidney transplantation: measurement, management and future considerations.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020Review
- Individualized intervention for frail non-dialysis elderly patients with chronic kidney disease: protocol for a randomized controlled trial.BMC geriatrics · 2020Article
- Validity and Reliability of the International Physical Activity Questionnaire in Chinese Hemodialysis Patients: A Multicenter Study in China.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Better Quality of Life of Peritoneal Dialysis compared to Hemodialysis over a Two-year Period after Dialysis Initiation.Scientific reports · 2019Article
- Use of the KDQOL-36™ for assessment of health-related quality of life among dialysis patients in the United States.BMC nephrology · 2019Observational
- Frailty Screening in Chronic Kidney Disease: Current Perspectives.International journal of nephrology and renovascular disease · 2019Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHealth-related quality of life (HRQoL) surveys are needed to evaluate regional and ethnic specificies. The aim of the present study was to evaluate the differences in HRQoL, frailty, and disability according to dialysis modality in the Korean population. PATIENTS AND
methodsWe enrolled relatively stable maintenance dialysis patients. A total of 1,616 patients were recruited into our study. The demographic and laboratory data collected at enrollment included age, sex, comorbidities, frailty, disability, and HRQoL scales.
resultsA total of 1,250 and 366 participants underwent hemodialysis (HD) and peritoneal dialysis (PD), respectively. The numbers of participants with pre-frailty and frailty were 578 (46.2%) and 422 (33.8%) in HD patients, and 165 (45.1%) and 137 (37.4%) in PD patients, respectively (P = 0.349). Participants with a disability included 195 (15.6%) HD patients and 109 (29.8%) PD patients (P < 0.001). On multivariate analysis, the mean physical component scale (PCS) and mental component scale (MCS), symptom/problems, and sleep scores were higher in HD patients than in PD patients. Cox regression analyses showed that an increased PCS in both HD and PD patients was positively associated with patient survival and first hospitalization-free survival. An increased MCS in both HD and PD patients was positively associated with first hospitalization-free survival only.
conclusionThere was no significant difference in frailty between patients treated with the two dialysis modalities; however, disability was more common in PD patients than in HD patients. The MCS and PCS were more favorable in HD patients than in PD patients. Symptom/problems, sleep, quality of social interaction, and social support were more favorable in HD patients than in PD patients; however, patient satisfaction and dialysis staff encouragement were more favorable in PD patients than in HD patients.
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