Trial reportNutrients2017
The Effect of a Mediterranean Diet on the Incidence of Cataract Surgery.
Trial report in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Influence of Diet, Dietary Products and Vitamins on Age-Related Cataract Incidence: A Systematic Review.Nutrients · 2023Pooled it
- Pooled it
- Article
- Associations between the Mediterranean lifestyle and incident age-related eye diseases: a longitudinal analysis from the UK Biobank.Journal of global health · 2026Article
- Association between dietary magnesium intake and risk of cataract surgery: data from NHANES 2003-2008.Eye (London, England) · 2025Article
- Dietary-related characteristics and cataract risk: evidence from a mendelian randomization study.Experimental biology and medicine (Maywood, N.J.) · 2025Article
- Association between dietary inflammation index and cataract: a population-based study from NHANES 2005-2008.Frontiers in nutrition · 2024Article
- Development and construction of a cataract risk prediction model based on biochemical indices: the National Health and Nutrition Examination Survey, 2005-2008.Frontiers in medicine · 2024Article
- Fruit and vegetable intake and the risk of cataract: insights from the UK Biobank study.Eye (London, England) · 2023Article
- Vitamin K and the Visual System-A Narrative Review.Nutrients · 2023Review
- Association between Healthy Eating Index-2015 and Age-Related Cataract in American Adults: A Cross-Sectional Study of NHANES 2005-2008.Nutrients · 2022Article
- Effect of Intelligent Operating Hole Towel in Cataract Patients.Computational intelligence and neuroscience · 2022Article
- Healthy Diet for Healthy Aging.Nutrients · 2021Review
- Traditional and Dairy Products and Vegetables Dietary Patterns Are Inversely Associated with the Risk of Cataract in the Middle Age and Aged Population: A Case-Control Study.The journal of nutrition, health & aging · 2021Article
- How fragile are Mediterranean diet interventions? A research-on-research study of randomised controlled trials.BMJ nutrition, prevention & health · 2021Article
- Dietary Patterns, Carbohydrates, and Age-Related Eye Diseases.Nutrients · 2020Review
- Experimental Outcomes of the Mediterranean Diet: Lessons Learned from the Predimed Randomized Controlled Trial.Nutrients · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCataract is a leading cause of vision impairment worldwide, and surgery is the only available treatment. The process that initiates lens opacification is dependent on the oxidative stress experienced by the lens components. A healthy overall dietary pattern, with the potential to reduce oxidative stress, has been suggested as a means to decrease the risk of developing cataract. We aimed to investigate the hypothesis that an intervention with a Mediterranean diet (MedDiet) rather than a low-fat diet could decrease the incidence of cataract surgery in elderly subjects.
methodsWe included 5802 men and women (age range: 55-80 years) from the Prevención con Dieta Mediterránea study (multicenter, parallel-group, randomized controlled clinical trial) who had not undergone cataract surgery. They were randomly assigned to one of three intervention groups: (1) a MedDiet enriched with extra-virgin olive oil (EVOO) (
resultsDuring a follow-up period of 7.0 years (mean follow-up period: 5.7 years; median: 5.9 years), 559 subjects underwent cataract surgery. Two hundred and six participants from the MedDiet + EVOO group, 174 from the MedDiet + Nuts group, and 179 from the control group underwent cataract surgery. We did not observe a reduction in the incidence of cataract surgery in the MedDiet groups compared to the control group. The multivariable adjusted hazard ratios were 1.03 (95% confidence interval [CI]: 0.84-1.26,
conclusionsTo our knowledge, this is the first large randomized trial assessing the role of a MedDiet on the incidence of cataract surgery. Our results showed that the incidence of cataract surgery was similar in the MedDiet with EVOO, MedDiet with nuts, and low-fat diet groups. Further studies are necessary to investigate whether a MedDiet could have a preventive role in cataract surgery.
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