Evidence map›Paper›PMID 28467029›Full record

ArticleAngewandte Chemie (International ed. in English)2017

Mizoroki-Heck Cyclizations of Amide Derivatives for the Introduction of Quaternary Centers.

Jose M Medina, Jesus Moreno, Sophie Racine, Shuaijing Du, Neil K Garg

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jose M MedinaDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Jesus MorenoDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Sophie RacineDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Shuaijing DuDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Neil K GargDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, CA, 90095, USA.

Funding

NEW DIRECTIONS IN CROSS- COUPLINGS CATALYZED BY NON- PRECIOUS METALSR01GM117016 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GARG, NEIL K · 2016 to 2019
$1.6M
Time-of-Flight Mass Spectrometer for Synthesis Supporting Biomedical ResearchS10RR025631 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HOUK, KENDALL N · 2009 to 2009
$328k
Synthesis of Bioactive Indoline-Containing Natural ProductsF31GM113642 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MORENO, JESUS · 2015 to 2017
$91k
NCRR NIH HHS S10 RR025631NIGMS NIH HHS F31 GM113642NIGMS NIH HHS R01 GM117016
6 · The paper itself

Abstract

We report non-decarbonylative Mizoroki-Heck reactions of amide derivatives. The transformation relies on the use of nickel catalysis and proceeds using sterically hindered tri- and tetrasubstituted olefins to give products containing quaternary centers. The resulting polycyclic or spirocyclic products can be obtained in good yields. Moreover, a diastereoselective variant of this method gives access to an adduct bearing vicinal, highly substituted sp

Indexed as

AmidesCatalysisCyclizationLigandsNickelAmidesLigandsNickelamideshomogeneous catalysisMizoroki-Heck reactionsnickelquaternary centers

Identifiers

PMID28467029
PMCPMC5669036

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.