ArticleNature communications2017
Arabidopsis proteins with a transposon-related domain act in gene silencing.
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- A functional atlas of transposon-encoded products and their integration into host networks.Nature communications · 2026Article
- Major alleles of CDCA7 shape CG methylation in Arabidopsis thaliana.Nature plants · 2025Article
- MAIL proteins prevent Polycomb silencing to keep genes active.Nature plants · 2025Article
- Plant mobile domain protein-DNA motif modules counteract Polycomb silencing to stabilize gene expression.Nature plants · 2025Article
- Phased secondary small interfering RNAs inNAR genomics and bioinformatics · 2023Article
- Article
- RTEL1 is required for silencing and epigenome stability.Nucleic acids research · 2023Article
- Chromatin remodeling of histone H3 variants underlies epigenetic inheritance of DNA methylation.bioRxiv : the preprint server for biology · 2023Article
- The large GTPase AtGBPL3 links nuclear envelope formation and morphogenesis to transcriptional repression.Nature plants · 2023Article
- Plant mobile domain proteins ensure Microrchidia 1 expression to fulfill transposon silencing.Life science alliance · 2023Article
- Plant Metabolic Engineering by Multigene Stacking: Synthesis of Diverse Mogrosides.International journal of molecular sciences · 2022Article
- Review
- Recent Acquisition of Functional m6A RNA Demethylase Domain in Orchid Ty3/Gypsy Elements.Frontiers in plant science · 2022Article
- Review
- RNA-directed DNA methylation prevents rapid and heritable reversal of transposon silencing under heat stress in Zea mays.PLoS genetics · 2021Article
- DNA polymerase epsilon is required for heterochromatin maintenance in Arabidopsis.Genome biology · 2020Article
- The plant mobile domain proteins MAIN and MAIL1 interact with the phosphatase PP7L to regulate gene expression and silence transposable elements in Arabidopsis thaliana.PLoS genetics · 2020Article
- Article
- Dark-Induced Senescence Causes Localized Changes in DNA Methylation.Plant physiology · 2020Article
- Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transposable elements (TEs) are prevalent in most eukaryotes, and host genomes have devised silencing strategies to rein in TE activity. One of these, transcriptional silencing, is generally associated with DNA methylation and short interfering RNAs. Here we show that the Arabidopsis genes MAIL1 and MAIN define an alternative silencing pathway independent of DNA methylation and short interfering RNAs. Mutants for MAIL1 or MAIN exhibit release of silencing and appear to show impaired condensation of pericentromeric heterochromatin. Phylogenetic analysis suggests not only that MAIL1 and MAIN encode a retrotransposon-related plant mobile domain, but also that host plant mobile domains were captured by DNA transposons during plant evolution. Our results reveal a role for Arabidopsis proteins with a transposon-related domain in gene silencing.
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