Evidence map›Paper›PMID 28466655›Full record

ArticleAging & mental health2018

Pain interference and depressive symptoms in communicative people with Alzheimer's disease: a pilot study.

Jinjiao Wang, Mary S Dietrich, Sandra F Simmons, Ronald L Cowan, Todd B Monroe

Open access · greenAbstract read
In one paragraph

Article in Aging & mental health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Nurses' Pain Management Competency in Nursing Home Residents With Dementia.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2026
    Article
  5. Article
  6. Mechanisms of comorbidity between Alzheimer's disease and pain.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  7. Article
  8. Article
  9. Pain Management in Home Health Care: Relationship With Dementia and Facility Admissions.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jinjiao Wanga Vanderbilt University School of Nursing , Nashville , TN , USA.
Mary S Dietricha Vanderbilt University School of Nursing , Nashville , TN , USA.
Sandra F Simmonsc Center for Quality Aging , Vanderbilt University Medical Center , Nashville , TN , USA.
Ronald L Cowanb Vanderbilt University School of Medicine , Nashville , TN , USA.
Todd B Monroea Vanderbilt University School of Nursing , Nashville , TN , USA.
Vanderbilt University · USVanderbilt University Medical Center · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR) KL2KL2RR024977 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$3.0M
Brain Activation and Pain Reports in People with Alzheimer's DiseaseK23AG046379 · NIA · VANDERBILT UNIVERSITY · PI MONROE, TODD BRYANT · 2015 to 2018
$627k
Age-Related Differences in Psychophysical and Neurobiological Response to PainR21AG045735 · NIA · VANDERBILT UNIVERSITY · PI COWAN, RONALD L, MONROE, TODD BRYANT · 2014 to 2015
$426k
NCRR NIH HHS KL2 RR024977NIA NIH HHS K23 AG046379NIA NIH HHS L30 AG045540NIA NIH HHS R21 AG045735
6 · The paper itself

Abstract

objectivesTo examine pain interference in verbally communicative older adults with mild to moderate Alzheimer's disease (AD) and to examine the association of pain interference with cognitive function and depressive symptoms.

methodFor this pilot study, we used a cross-sectional design to examine pain interference (Brief Pain Inventory-Short Form), cognitive function (Mini-Mental State Exam), and depressive symptoms (15-item Geriatric Depression Scale) in 52 older (≥65) communicative adults with AD who reported being free from chronic pain requiring daily analgesics.

resultsPain was reported to interfere with general activity (13.5%), mood (13.5%), walking ability (13.5%), normal work (11.5%), enjoyment of life (11.5%), relationships with other people (9.6%), and sleep (9.6%). Pain interference was significantly positively correlated with both cognitive function (r

conclusionAmong older people with AD who report being free from chronic pain requiring daily analgesics, 2 in 10 are at risk of pain interference and depressive symptoms. Those with better cognitive function reported more pain interference and depressive symptoms, meaning pain is likely to be under-reported as AD progresses. Clinicians should regularly assess pain interference and depressive symptoms in older persons with AD to identify pain that might be otherwise overlooked..

Indexed as

Alzheimer DiseaseActivities of Daily LivingAgedAged, 80 and overCommunicationComorbidityCross-Sectional StudiesDepressionFemaleHumansIndependent LivingInterpersonal RelationsMalePainPilot Projectscommunity dwelling adults with dementiaDementiaend-of-lifepain assessment

Identifiers

PMID28466655
PMCPMC6370478
OpenAlexW2611147181

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.