Evidence map›Paper›PMID 28466442›Full record

ArticleVirologica Sinica2017

Viral metagenomics analysis of feces from coronary heart disease patients reveals the genetic diversity of the Microviridae.

Lianghua Guo, Xiuguo Hua, Wen Zhang, Shixing Yang, Quan Shen, Haibing Hu, Jingjiao Li, Zhijian Liu, Xiaochun Wang, Hua Wang and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Virologica Sinica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Lianghua GuoSchool of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China.
Xiuguo HuaSchool of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China.
Wen ZhangSchool of Medicine, Jiangsu University, Zhenjiang, 212013, China.
Shixing YangSchool of Medicine, Jiangsu University, Zhenjiang, 212013, China.
Quan ShenSchool of Medicine, Jiangsu University, Zhenjiang, 212013, China.
Haibing HuSchool of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China.
Jingjiao LiSchool of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China.
Zhijian LiuSchool of Medicine, Jiangsu University, Zhenjiang, 212013, China.
Xiaochun WangSchool of Medicine, Jiangsu University, Zhenjiang, 212013, China.
Hua WangSchool of Medicine, Jiangsu University, Zhenjiang, 212013, China.
Chenglin ZhouDepartment of Laboratory Medicine, Jiangsu Taizhou People's Hospital, Taizhou, 225300, China.
Li CuiSchool of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, 200240, China. lcui@sjtu.edu.cn.
Jiangsu University · CNShanghai Jiao Tong University · CNNantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have declared that members of the ssDNA virus family Microviridae play an important role in multiple environments, as they have been found taking a dominant position in the human gut. The aim of this study was to analyze the overall composition of the gut virome in coronary heart disease (CHD) patients, and try to discover the potential link between the human gut virome and CHD. Viral metagenomics methods were performed to detect the viral sequences in fecal samples collected from CHD inpatients and healthy persons as controls. We present the analysis of the virome composition in these CHD patients and controls. Our data shows that the virome composition may be linked to daily living habits and the medical therapy of CHD. Virgaviridae and Microviridae were the two dominant types of viruses found in the enteric virome of CHD patients. Fourteen divergent viruses belonging to the family Microviridae were found, twelve of which were grouped into the subfamily Gokushovirinae, while the remaining two strains might represent two new subfamilies within Microviridae, according to the phylogenetic analysis. In addition, the genomic organization of these viruses has been characterized.

Indexed as

BiodiversityAgedAged, 80 and overCoronary DiseaseFecesHumansMetagenomicsMiddle AgedVirusescoronary heart disease (CHD)Gokushovirinaegut viromeMicroviridaeviral metagenomics

Identifiers

PMID28466442
PMCPMC6598973
OpenAlexW2611463190

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.