ArticleClinical rheumatology2017
Evaluation of blood neutrophil-lymphocyte ratio and platelet distribution width as inflammatory markers in patients with fibromyalgia.
Article in Clinical rheumatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 65 citations in OpenAlex.
- Nutraceutical Supplementation as a Potential Non-Drug Treatment for Fibromyalgia: Effects on Lipid Profile, Oxidative Status, and Quality of Life.International journal of molecular sciences · 2024Trial
- Effect of vitamin B6 on pain, disease severity, and psychological profile of fibromyalgia patients; a randomized, double-blinded clinical trial.BMC musculoskeletal disorders · 2022Trial
- The Neutrophil-to-Lymphocyte Ratio in Fibromyalgia: A Systematic Review with a Neuroimmune Perspective.Brain sciences · 2026Review
- Assessment of the Concomitance of Fibromyalgia in Patients with Axial Spondyloarthritis and Rheumatoid Arthritis.Archives of rheumatology · 2026Article
- Development of a Novel 11-Gene Signature Related to Immune Subtypes for FibromyalgiaEndocrine, metabolic & immune disorders drug targets · 2026Article
- Elevated Monocyte-to-Lymphocyte and Platelet-to-Lymphocyte Ratios Are Associated with Disease Activity and Pain in Fibromyalgia: A Cross-Sectional Study.Journal of clinical medicine · 2025Article
- The onset inflammatory parameters and the Cobb angle in adolescent idiopathic scoliosis: a case-control study.Croatian medical journal · 2025Article
- The Role of Immature Granulocytes in Fibromyalgia: An Indicator of Subclinical Inflammation?Biomedicines · 2025Article
- Global Disease Control in Inflammatory Arthritis Patients with Fibromyalgia Multi-Failure to Biologic Drugs: Short-Term Impact of Target Therapies on Both Disease Courses.Journal of clinical medicine · 2025Article
- Evaluation of Eosinophil-to-Lymphocyte Ratio and Eosinophil Count as Predictive Markers in Fibromyalgia Syndrome.Pakistan journal of medical sciences · 2025Article
- Neutrophil-Lymphocyte Ratio in Fibromyalgia and Axial Spondyloarthritis: A Potential Biomarker for Diagnosis and Disease Activity.Biomedicines · 2025Article
- Evaluation of the role of inflammation in fibromyalgia through haematological indices: A retrospective study.The Indian journal of medical research · 2025Article
- Proinflammatory diet is associated with higher pain, disease severity and biochemical parameters associated with inflammation in fibromyalgia.Pain medicine (Malden, Mass.) · 2025Article
- Review
- Association between perioperative platelet distribution width changes and postoperative acute kidney injury in patients with renal insufficiency: a retrospective study.BMC nephrology · 2024Article
- Value of Diverse Hematological Markers in Fibromyalgia: A Real-World Study.Journal of clinical practice and research · 2024Article
- Inflammation, Autoimmunity, and Infection in Fibromyalgia: A Narrative Review.International journal of molecular sciences · 2024Review
- Effects of physical activity levels on characteristic pain in temporomandibular dysfunctions: a cross-sectional study.Head & face medicine · 2024Observational
- Factor Impacting Quality of Life Among Sepsis Survivors During and After Hospitalization: A Systematic Review of Current Empirical Evidence.Journal of multidisciplinary healthcare · 2024Review
- Chronic Postsurgical Pain in Children and Adolescents: A Call for Action.Journal of pain research · 2024Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fibromyalgia syndrome (FMS) is characterized by chronic widespread pain and systemic symptoms. The aetiology and pathogenesis of fibromyalgia are not yet fully understood. Blood neutrophil/lymphocyte ratio (NLR) is a marker of systemic inflammatory response. Platelet distribution width (PDW) and mean platelet volume (MPV) are the determinants of platelet activation and studied as markers in inflammatory diseases. The aim of the present study was to evaluate levels of NLR,PDW and MPV in patients with fibromyalgia. A total of 197 FMS patients and 53 healthy controls are included in the study. Demographic characteristics, erythrocyte sedimentation rate, C-reactive protein, neutrophil, lymphocyte and platelet counts, platelet distribution width and mean platelet volume levels were recorded. In the patient group, the blood NLR and MPV were significantly higher and the PDW was significantly lower compared to the control group. In the roc curve analysis, blood PDW ≥had 90.4% sensitivity and 90% specificity in predicting fibromyalgia. The results of this study suggest NLR and PDW as promising inflammatory markers indicating fibromyalgia and may be beneficial in facilitating the diagnosis of FMS patients.
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