Evidence map›Paper›PMID 28466407›Full record

ArticleHead and neck pathology2017

Rhabdomyosarcoma, Spindle Cell/Sclerosing Variant: A Clinical and Histopathological Examination of this Rare Variant with Three New Cases from the Oral Cavity.

Molly Housley Smith, Daniel Atherton, John D Reith, Nadim M Islam, Indraneel Bhattacharyya, Donald M Cohen

Abstract readCase Reports
In one paragraph

Article in Head and neck pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Sclerosing Rhabdomyosarcoma of the Parotid Gland in a Child- A Rare Case Report.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Small Round Blue Cell Tumours of the Sinonasal Area: Our 5 year Experience in a Tertiary Care Centre in India.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  9. Article
  10. Article
  11. Spindle cell rhabdomyosarcoma in the adult: A rare case report.Journal of oral and maxillofacial pathology : JOMFP · 2022
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Molly Housley SmithDivision of Oral and Maxillofacial Pathology, University of Florida College of Dentistry, 1395 Center Dr., Gainesville, FL, 32610-0414, USA. Mhousley@dental.ufl.edu.ORCID http://orcid.org/0000-0002-8502-4305
Daniel AthertonDepartment of Pathology, University of Alabama, HSB 175J, 619 19th St. South, Birmingham, AL, USA.
John D ReithDepartment of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL, USA.
Nadim M IslamDivision of Oral and Maxillofacial Pathology, University of Florida College of Dentistry, 1395 Center Dr., Gainesville, FL, 32610-0414, USA.
Indraneel BhattacharyyaDivision of Oral and Maxillofacial Pathology, University of Florida College of Dentistry, 1395 Center Dr., Gainesville, FL, 32610-0414, USA.
Donald M CohenDivision of Oral and Maxillofacial Pathology, University of Florida College of Dentistry, 1395 Center Dr., Gainesville, FL, 32610-0414, USA.
University of Florida · USUniversity of Alabama · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spindle cell/sclerosing rhabdomyosarcoma (S-ScRMS) was recently recognized in 2013 by the World Health Organization (WHO) as a stand-alone entity (Parham et al., WHO classification of tumours of soft tissue and bone, IARC Press, Lyon, 2013). Historically, the spindle cell and sclerosing variants were subcategorized under embryonal type rhabdomyosarcoma. Current data supports that certain S-ScRMS cases have a more aggressive clinical course with reduction of long-term survival, and those found in the head and neck region often exhibit extensive local recurrence. Furthermore, due to variable histopathologic appearances and immunohistochemical findings, misdiagnosis is common. We aim to report the variability in histopathologic patterns, immunohistochemical findings, radiographic features, and clinical data on three new cases of S-ScRMS presenting in the oral cavity of young adult males (ages 22, 24, and 39 years). The English-language literature on S-ScRMS is briefly reviewed as well.

Indexed as

AdultHumansMaleMouth NeoplasmsRhabdomyosarcoma, EmbryonalYoung AdultEmbryonalOral cavityRhabdomyosarcomaSclerosingSpindle cell

Identifiers

PMID28466407
PMCPMC5677073
OpenAlexW2610437573

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.