ArticleWorld journal of microbiology & biotechnology2017
Identification and characterization of the major antifungal substance against Fusarium Sporotrichioides from Chaetomium globosum.
Article in World journal of microbiology & biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- A novel endophytic Kineococcus from rice against Fusarium culmorum and Fusarium sporotrichioides and whole-genome analysis.Antonie van Leeuwenhoek · 2026Article
- Microbiome network remodeling is associated with soil lipid metabolism in safflower under different cropping system-location combinations: an omics-based dissection.Frontiers in microbiology · 2026Article
- Article
- Characterization of a β-N-acetylhexosaminidase CgNagase20 from Chaetomium globosum with antifungal activity against Fusarium sporotrichioides.World journal of microbiology & biotechnology · 2025Article
- A novel antifungal chitinase from Chaetomium globosum: column-free purification and characterization.Archives of microbiology · 2025Article
- Construction of an Efficient Engineered Strain for Chaetoglobosin A Bioresource Production from Potato Starch Industrial Waste.Foods (Basel, Switzerland) · 2025Article
- Article
- Three New Species and Five New Host Records fromJournal of fungi (Basel, Switzerland) · 2024Article
- Characterization and development of transcriptome-derived novel EST-SSR markers to assess genetic diversity in3 Biotech · 2023Article
- Diversity and Biocontrol Potential of Endophytic Fungi and Bacteria Associated with Healthy Welsh Onion Leaves in Taiwan.Microorganisms · 2023Article
- Article
- Identification of a Novel Pleiotropic Transcriptional Regulator Involved in Sporulation and Secondary Metabolism Production inInternational journal of molecular sciences · 2022Article
- New insight into the production improvement and resource generation of chaetoglobosin A in Chaetomium globosum.Microbial biotechnology · 2022Article
- Temporal transcriptome of tomato elucidates the signaling pathways of induced systemic resistance and systemic acquired resistance activated byFrontiers in genetics · 2022Article
- Investigation of biological activity of soil fungal extracts and LC/MS-QTOF based metabolite profiling.Scientific reports · 2021Article
- Transcriptome Reprogramming of Tomato Orchestrate the Hormone Signaling Network of Systemic Resistance Induced byFrontiers in plant science · 2021Article
- Transcriptome Profiling Provides Insights Into Potential Antagonistic Mechanisms Involved inFrontiers in microbiology · 2020Article
- Bioactivities and Future Perspectives of Chaetoglobosins.Evidence-based complementary and alternative medicine : eCAM · 2020Review
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fusarium sporotrichioides, is a common soil-borne plant pathogen causing dry rot of potato in Northeast China. The objective of this study was to identify the main antifungal substances from Chaetomium globosum W7 against F. sporotrichioides. Strain W7 can significantly inhibit F. sporotrichioides without direct contact, suggesting that its antifungal substance was extracellular, and the solubility of this antifungal substance in ethyl acetate was superior to that in water. Acetone was selected as the optimum solvent for the extraction of the metabolites of C. globosum. Metabolites were then separated with thin-layer chromatography. Following antifungal tests on bands, a dark brown band with Rf value of 0.20 was determined as the antifungal substance, and identified as chaetoglobosin A. The antifungal activity test showed that the minimum inhibitory concentration of chaetoglobosin A to F. sporotrichioides was 9.45-10.50 μg/mL, IC50 being 4.344 μg/mL. Chaetoglobosin A also proved to have an excellent preventive effect on potato dry rot caused by F. sporotrichioides. To summarize, chaetoglobosin A was identified as the main active substance of C. globosum to inhibit F. sporotrichioides for the first time, and demonstrated a potential application value in agriculture.
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