ArticleEcotoxicology (London, England)2017
Effect of pure microcystin-LR on activity and transcript level of immune-related enzymes in the white shrimp (Litopenaeus vannamei).
Article in Ecotoxicology (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 58 citations in OpenAlex.
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- Comparative analysis of crab growth performance, enzyme activity, and microbiota between rice-crab coculture and pond farming systems.Frontiers in veterinary science · 2025Article
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- Effects of Dietary Bio-Fermented Selenium Supplementation on Growth, Immune Performance, and Intestinal Microflora of Chinese Mitten Crabs,International journal of molecular sciences · 2024Article
- Understanding the Risks of Diffusion of Cyanobacteria Toxins in Rivers, Lakes, and Potable Water.Toxins · 2023Review
- Subchronic Toxicity of Microcystin-LR on Young Frogs (Frontiers in microbiology · 2022Article
- Integration of metagenomic and metabolomic insights into the effects of microcystin-LR on intestinal microbiota ofFrontiers in microbiology · 2022Article
- Satellite-Based Monitoring of the Algal Communities of Aras Dam Reservoir: Meteorological Dependence Analysis and the Footprint of COVID-19 Pandemic Lockdown on the Eutrophication Status.International journal of environmental research · 2022Article
- The Molecular Mechanism of Hemocyte Immune Response inFrontiers in microbiology · 2021Article
- A Comparative Study on Growth and Metabolism ofFrontiers in physiology · 2020Article
- Individual and combined effects of salinity and lipopolysaccharides on the immune response of juvenile Takifugu fasciatus.Fish physiology and biochemistry · 2019Article
- Nitrite Enhances MC-LR-Induced Changes on Splenic Oxidation Resistance and Innate Immunity in Male Zebrafish.Toxins · 2018Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microcystins (MCs) in freshwater and marine waters released by toxin-producing cyanobacteria have negative impacts to the aquatic environment. This study aimed to investigate the effect of pure microcystin-LR on activity and transcript level of immune-related enzymes in the white shrimp Litopenaeus vannamei. After exposed to varying concentrations of pure microcystin-LR (MC-LR) for 30 days, the activity of superoxide dismutase (SOD), lysozyme (LZM), glutathione peroxidase (GPx), peroxidase (POD), acid phosphatase (ACP), alkaline phosphatase (AKP) and transcript level of cMn-sod, lzm, gpx were investigated in the hepatopancreas of white shrimp (L. vannamei). Immune-related enzyme activities responded differently to MC-LR exposure. SOD, GPx, and POD activity in the hepatopancreas were activated in a concentration-dependent manner while LZM activity was significantly inhibited in the treatment groups. ACP and AKP activity showed an increase, followed by a decrease. The transcript levels of cMn-sod, lzm, and gpx were consistent with changes in their encoding enzyme activity. These results demonstrated that sub-chronical exposure to MC-LR induced the alteration of immune-related enzymes and corresponding genes in the hepatopancreas, which may help explain the presence of detoxification mechanisms in crustaceans and how they were protected from MC-LR stress for a long period of time.
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