Evidence map›Paper›PMID 28466195›Full record

Trial reportLasers in medical science2017

Beneficial neurocognitive effects of transcranial laser in older adults.

Enrique Vargas, Douglas W Barrett, Celeste L Saucedo, Li-Da Huang, Jacob A Abraham, Hirofumi Tanaka, Andreana P Haley, F Gonzalez-Lima

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Lasers in medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07224607 (A Longitudinal Study Investigating the Effects of Photobiomodulation), which is not on this map. Cited by 67 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07224607 narecruitingnot on this mapstarted 2025, after this paper: background citation

A Longitudinal Study Investigating the Effects of Photobiomodulation (PBM) on Cognitive Function and Alzheimer's Disease (AD)-Related Biomarkers in Individuals With Mild Cognitive Impairment (MCI) or Dementia Due to AD

TypeinterventionalSponsorCedars-Sinai Medical CenterRan2025 to 2026Enrolled45ConditionsAlzheimer's DiseaseArmsPhotobiomodulation
3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Photobiomodulation improves the frontal cognitive function of older adults.International journal of geriatric psychiatry · 2019
    Trial
  11. Trial
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Enrique VargasDepartment of Psychology and Institute for Neuroscience, University of Texas at Austin, Austin, TX, 78712, USA.
Douglas W BarrettDepartment of Psychology and Institute for Neuroscience, University of Texas at Austin, Austin, TX, 78712, USA.
Celeste L SaucedoDepartment of Psychology and Institute for Neuroscience, University of Texas at Austin, Austin, TX, 78712, USA.
Li-Da HuangDepartment of Electrical Engineering, University of Texas at Austin, Austin, TX, 78712, USA.
Jacob A AbrahamDepartment of Electrical Engineering, University of Texas at Austin, Austin, TX, 78712, USA.
Hirofumi TanakaDepartment of Kinesiology and Health Education, University of Texas at Austin, Austin, TX, 78712, USA.
Andreana P HaleyDepartment of Psychology and Institute for Neuroscience, University of Texas at Austin, Austin, TX, 78712, USA.
F Gonzalez-LimaDepartment of Psychology and Institute for Neuroscience, University of Texas at Austin, Austin, TX, 78712, USA. gonzalezlima@utexas.edu.

Funding

Cognitive Enhancement Through Transcranial Laser TherapyR21AG050898 · NIA · UNIVERSITY OF TEXAS AT AUSTIN · PI HALEY, ANDREANA PETROVA · 2016 to 2017
$426k
NIA NIH HHS R21 AG050898
6 · The paper itself

Abstract

Transcranial infrared laser stimulation (TILS) at 1064 nm, 250 mW/cm

Indexed as

LasersAgedAged, 80 and overAgingBrainCarotid Intima-Media ThicknessCognitionElectroencephalographyFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedOxygenPilot ProjectsPrefrontal CortexOxygenAttentionBrain photobiomodulationEEGfMRIInfrared laserMemory

Identifiers

PMID28466195
PMCPMC6802936

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.