ReviewHernia : the journal of hernias and abdominal wall surgery2017
Critical overview of all available animal models for abdominal wall hernia research.
Review in Hernia : the journal of hernias and abdominal wall surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Inadequate awareness of adherence to ARRIVE guidelines, regarding reporting quality of hernia models repaired with meshes: a systematic review.Hernia : the journal of hernias and abdominal wall surgery · 2022Pooled it
- META Score: An International Consensus Scoring System on Mesh-Tissue Adhesions.World journal of surgery · 2020Guideline
- Extended validation of the mesh integration (MINT) index: a 1-year porcine study.Surgical endoscopy · 2026Article
- Validation of a rat parastomal hernia model for evaluating mesh biocompatibility and repair outcomes.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- How do we evaluate the remodeling and regeneration of absorbable meshes? Multi-dimensional evaluation parameters from multi-species.Hernia : the journal of hernias and abdominal wall surgery · 2026Review
- Validating the mesh integration (MINT) index: a 3-month porcine study.Surgical endoscopy · 2026Article
- Introducing the Mesh Integration (MINT) Index: a standardised ratio scale for assessing in vivo hernia mesh performance.Surgical endoscopy · 2025Article
- Experimental methodology used for testingRSC advances · 2025Review
- Collagen Remodeling of Strattice™ Firm in a Nonhuman Primate Model of Abdominal Wall Repair.Bioengineering (Basel, Switzerland) · 2025Article
- A reproducible rat model for predicting incisional hernia recurrence: insights for clinical translation.Scientific reports · 2025Article
- Standardization of laparoscopic intraperitoneal onlay mesh repair for incisional hernia: Impact on clinical outcome and quality-of-life (LIPOM trial, NCT 02089958).Contemporary clinical trials communications · 2025Article
- Part II: understanding pain in pigs-pain assessment in pigs with spontaneously occurring diseases or injuries.Porcine health management · 2025Review
- Biomechanical evaluation of prophylactic reinforcement of the linea alba with a novel method of positioning and fixation of polypropylene mesh, in an animal model.Acta cirurgica brasileira · 2025Article
- Establishment and evaluation of rat models of parastomal hernia.Hernia : the journal of hernias and abdominal wall surgery · 2024Article
- Safety and tissue remodeling assay of small intestinal submucosa meshes using a modified porcine surgical hernia model.Scientific reports · 2024Article
- A Novel Bio-Adhesive Mesh System for Medical Implant Applications: In Vivo Assessment in a Rabbit Model.Gels (Basel, Switzerland) · 2023Article
- Practical Mouse Model to Investigate Therapeutics for Staphylococcusaureus Contaminated Surgical Mesh Implants.The Journal of surgical research · 2023Article
- A Simplified Abdominal Wall Model to Teach Complex Abdominal Wall Reconstruction.Plastic and reconstructive surgery. Global open · 2022Article
- The experimental methodology and comparators used for in vivo hernia mesh testing: a 10-year scoping review.Hernia : the journal of hernias and abdominal wall surgery · 2022Article
- In Vivo Evaluation of a Pectin-Honey Hydrogel Coating on Polypropylene Mesh in a Rat Model of Acute Hernia.Gels (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSince the introduction of the first prosthetic mesh for abdominal hernia repair, there has been a search for the "ideal mesh." The use of preclinical or animal models for assessment of necessary characteristics of new and existing meshes is an indispensable part of hernia research. Unfortunately, in our experience there is a lack of consensus among different research groups on which model to use. Therefore, we hypothesized that there is a lack of comparability within published animal research on hernia surgery due to wide range in experimental setup among different research groups.
methodsA systematic search of the literature was performed to provide a complete overview of all animal models published between 2000 and 2014. Relevant parameters on model characteristics and outcome measurement were scored on a standardized scoring sheet.
resultsDue to the wide range in different animals used, ranging from large animal models like pigs to rodents, we decided to limit the study to 168 articles concerning rat models. Within these rat models, we found wide range of baseline animal characteristics, operation techniques, and outcome measurements. Making reliable comparison of results among these studies is impossible.
conclusionThere is a lack of comparability among experimental hernia research, limiting the impact of this experimental research. We therefore propose the establishment of guidelines for experimental hernia research by the EHS.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.